Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . July 6th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Safety - Most countries fall short of ensuring a safe blood supply
Tissue Engineering - Osteoblast adherence and migration efficacy differs depending on titanium surface type
Tissue Engineering - TGF-beta 1 immobilized tri-co-polymer developed for articular cartilage tissue engineering
Tissue Engineering - UV-embossed micropattern scaffolds control cell shape and muscle cell orientation
Acute Lymphoblastic Leukemia - Adult acute lymphoblastic leukemia with dic(7:9) demonstrate consistent phenotype
Acute Myelogenous Leukemia - CuraGen and TopoTarget announce NCI-sponsored Phase II clinical trial with PXD101 for AML
Angiology - Coronary artery bypass graft critical occlusion pressure measurement is discussed
Angiology - Culture-expanded endothelial progenitor cells may hasten new vessel growth
Angiology - Experimental endotoxemic acute renal failure protected against by levosimendan
Apnea - Obstructive sleep-disordered breathing in children may not correlate with VEGF
Apoptosis - Apoptosis is inhibited by a dominant negative form of p63
Bacterial Meningitis - MMP-9 and MMP-8/-13 are upregulated in CSF during aseptic and bacterial meningitis
Bladder Cancer - GnT-V and its resultant oligosaccharides associated with good prognosis in bladder cancer
Bone Formation - Cbl-b downregulates bone formation via in osteoblasts during denervation
Breast Cancer - Hypoxia inducible factor-1 alpha is prognostic marker in breast cancer subgroup
Business Update - Dainippon Sumitomo and Chelsea Therapeutics sign licensing agreement for hypotension agent
Business Update - Dr. Bernard Salick forms Salick Cardiovascular Centers to offer outpatient-focused services
Business Update - SuperGen completes contract to transition distribution of leukemia injection outside U.S.
Business Update - Sysmex receives package order for hematology analyzers from Japanese Red Cross Society
Business Update - WellBound, Arnett Clinic sign agreement to establish self-care dialysis program
Cancer Therapy - Epoetin alfa dosing as initiation treatment in chemotherapy-related anemia studied
Cancer Therapy - Hsp90 inhibitors enhance activity of topoisomerase II poisons etoposide and mitoxantrone
Cardiac Medical Devices - CardioWest temporary Total Artificial Heart is newest option for patients awaiting transplant
Cardiac Medical Devices - Lipid Sciences initiates human trial to evaluate plasma delipidation system
Cardiovascular Disease - Thrombolytic therapy should not be withheld in pregnant patients
Cell Replacement Therapy - Embryonic stem cell differentiation into cardiomyocytes enhanced by combination techniques
Cell Therapy - Photodynamic therapy plus intratumoral naive DC injection induces antitumor immunity
Cervical Cancer - Low podoplanin expression predicts poor prognosis in advanced-stage squamous cell carcinoma
Clinical Trials - Aspirin-treated CAD patients show greater platelet inhibition with prasugrel vs. clopidogrel
Clinical Trials - Clinical data on Pharmion's satraplatin from two pharmacokinetics studies presented at ASCO
Clinical Trials - Clinical data on Pharmion's Vidaza (azacitidine for injectable suspension) presented at ASCO
Collaborations - Spectral, Toray Medical form therapeutic strategic alliance for severe sepsis management
Colorectal Cancer Biomarker - Fecal Adnab-9 binding is a colorectal neoplasia risk marker
Conjugated Vaccine Development - Method developed for obtaining conjugated vaccines
Coronary Artery Disease - Obesity is associated with increased carotid intima-media thickness in women
Developmental Biology - Developmental regulators suppressed in murine embryonic stem cells
Diabetic Retinopathy - Diabetic retinopathy progression involves angiogenic proteins and circulating progenitor cells
Diabetic Retinopathy - OptiMedica reports clinical data on PASCAL method of photocoagulation
Diagnostics - Cancer patients with suspected pulmonary embolism assessed by D-dimer testing
Drug Development - Clinical data on Ascenta Therapeutics' lead product AT-101 presented at ASCO
Drug Development - Data at ASCO demonstrate potential of Velcade for injection across solid and hematological cancers
Embryogenesis - Alginate-extracellular matrix gels investigate ovarian follicle development
Embryonic Stem Cell Research - Embryonic stem cell culture designed to facilitate cell-cell signaling
Embryonic Stem Cell Research - Serum-free medium improves efficacy of embryonic stem cell line cultivation
Emergency Medicine - Prothrombin complex concentrate provides immediate reversal of warfarin
Emergency Medicine - Stroke time to treatment with IV t-PA reduced with an ED triage strategy
Esophageal Variceal Bleeding - Debiopharm to initiate U.S. confirmatory trial of Sanvar in esophageal variceal bleeding
Facilities - African Institute for Transfusion Medicine opened by Safe Blood for Africa Foundation
Fitness & Wellness - Activity-dependent muscle growth requires resident stem cells
Fungemia Diagnostics - Invasive fungal infections in hematological cancers screened by noninvasive PCR
Gene Silencing - RNA interference-mediated gene silencing increased in embryonic carcinoma cells
Genetically Modified Cells - Genetically modified Schwann cells provide transplants in nerve regeneration
Genetics & Genomics - cDNA compared between dental pulp and mesenchymal stem cells
Genetics & Genomics - Clinical Data announces 2006 launch of genetic test for warfarin response
Graft-versus-Host Disease - AHSCT patients with chronic graft-versus-host disease are at risk of nephrotic syndrome
HIV/AIDS Diet & Nutrition - HIV-1-infected patients need higher retinol doses to compensate for urinary loss
HTLV-1-Associated HAM/TSP - HCD4 cells positive for NKG2D in HTLV-1-associated myelopathy/tropical spastic paraparesis
Hematology - Open-heart surgery patients show lower postop bleeding with tranexamic acid application
Hemophilia - Hemophilia patients can develop venous thrombosis with concentrate infusions
Hip Replacement - Proximal DVT risk after oncologic hip replacement reduced
Imaging - Noninvasive imaging detects cardiac leukemia after T cell ALL ASCT relapse
Immunosuppression - HEPA filtration does not decrease mortality among immunosuppressed cancer patients
Infectious Diseases - CAZ-R Klebsiella pneumoniae infections have a greater mortality risk when therapy is delayed
Islet Transplantation - Immunosuppressants increase insulin independence after islet transplantation
Kidney Transplantation - Chronic allograft nephropathy is potentially prevented with exogenous BMP7
Kidney Transplantation - Soluble CD30 levels predict increased risk of early acute rejection after kidney transplant
Leukemia - Lymphoma and leukemia diagnosed by endoscopic ultrasound-guided fine-needle aspiration biopsy
Leukemia - Refractory or relapsed acute lymphoblastic leukemia treated by clofarabine
Liver Transplantation - Hepatopulmonary syndrome increases post-op mortality rate after liver transplantation
Liver Transplantation - Liver transplantation in Mdr2+/- mice complicated by bile salt toxicity
Liver Transplantation - Progressive histological damage occurs in pediatric liver allografts
Lung Cancer - Bcl-2 positivity predicts overall survival in advanced non-small cell lung cancers
Lung Cancer - Putative oncogenes identified in lung adenocarcinoma
Lung Cancer - TTF-1 does not predict survival in stage III non-small cell lung cancer
Lymphoma - NK/T-cell lymphoma 'nasal type' is rare in Italian population and carries a poor prognosis
Malaria - TNF-alpha overproduction in malaria associated with enhanced malarial anemia
Mantel Cell Lymphoma - Clinical study shows efficacy of single-agent Velcade in treating mantle cell lymphoma
Medical Devices - VNUS Medical Technologies reports first human treatment with new venous catheter
Melanoma - Melanoma metastases express functional CXCR4
Mergers & Acquisitions - Haemonetics to acquire Arryx in $26 million transaction
Morbid Obesity - Soluble CD40L decreases in patients with morbid obesity after bariatric surgery
Multiple Myeloma - Multiple myeloma cell growth predominantly stimulated by bone-derived IGFs
Myeloma - Early multiple myeloma diagnosis and patient referral to oncologist recommended
Myeloma - Leukemia & Lymphoma Society introduces education series for myeloma patients
Myocardial Infarction - AMI patients treated with GP IIb/IIIa antagonists during PCI show reduced late mortality
Natural Products - Essential oil extracts from Thai medicinal plants proposed for cancer treatment
Nerve Regeneration - Nerve allograft treatment with FK506 induces better regeneration than other immunosuppressants
Neuroprotection - Autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection
Neuroscience - Amyloid precursor protein is involved in neural progenitor cell differentiation
Neuroscience - Focal cerebral ischemic damage can be salvaged by hemoglobin polymer transfusion
Obesity Pathogenesis - Adiponectin and insulin sensitivity mediate favorable effects of low body fat mass on blood lipids
Obstetrics - Sickle cell trait in pregnant women does not increase susceptibility to bacteriuria
Orthopedics - Total knee arthroplasty blood flow preservation is not improved with either MA or LA technique
Patents - SuperGen receives U.S. patent for its formulation of pentostatin for injection
Pediatric Acute Myeloid Leukemia - Seven genes monitor minimal residual disease in pediatric acute myeloid leukemia
Pediatric Cardiology - Mechanical heart valve replacement in children with valve disease is a valuable option
Pediatric Oncology - Childhood cancer incidence in Ontario trended and projected
Photopheresis - Photopheresis is a therapeutic alternative for solid organ transplant patients
Photoradiation - Photoradiation inhibits survival of hepatoma cells
Polycystic Ovary Syndrome - Metformin may lower coronary risk in hyperinsulinemic women with polycystic ovary syndrome
Post-Transplantation Lymphoproliferative Disorder - PTLD incidence high in pediatric solid organ transplantation
Prostate Cancer - Prostate-specific membrane antigen antibody-drug conjugate has potent antitumor activity
Respiratory Medicine - Acute lung injury pathogenesis may be linked to inducible nitric oxide synthase
Simian Parvovirus - Simian parvovirus infection in heart transplant recipients causes severe anemia-related death
Spermatogenesis - Spermatogenesis arrested by ubiquitin carboxyl-terminal hydrolase L1 overexpression
Spinal Cord Injury - Directed nerve regrowth after spinal cord injury induced by alginate-based ACH
Stem Cell Research - Angiogenic factors and transduction protein confer differentiation properties to endothelial cells
Stem Cell Research - Aqaporin-4 and -9 are expressed in adult subventricular zone-derived neural stem cells
Stem Cell Research - Cartilage progenitor cells are present in the adult ear perichondrium
Stem Cell Research - Functional neural structures generated by inkjet printing method
Stem Cell Research - Hepatic progenitor cell proliferation is inhibited by interferon alpha
Stem Cell Research - Melanoma inhibitory activity regulates chondrogenesis and cartilage maintenance
Stem Cell Research - Neural stem cell proliferation decreased in schizophrenia but not depression
Stem Cell Research - Pancreatic progenitor cell expansion is regulated by bone morphogenetic protein
Stem Cell Research - Pluripotent spermatogonial stem cells isolated from adult testis
Stem Cell Research - Transgenic Hydra allow tracking of individual stem cells during morphogenesis
Surgical Technology - Atypical pulmonary embolism of port catheter fragments in oncology patients described
Thrombotic Thrombocytopenic Purpura - Rituximab may decrease treatment failure rates in thrombotic thrombocytopenic purpura
Tissue Engineering - Transplantable retinal pigment epithelial cell sheet fabrication analyzed
Transplant Medicine - Changes in the transcriptome detected in allograft rejection
Transplant Medicine - Preservation injury may target subcellular endoplasmic reticulum early
Transplant-Related Arteriosclerosis - Angiotensin II may play a role in pathogenesis of transplant arteriosclerosis
Trypanosoma Cruzi Pathogenesis - Trypanosoma cruzi disrupts myofibrillar organization in neonatal cardiomyocytes
Venous Thromboembolism - Incidence of venous thromboembolism during pregnancy may be higher than reported
Angiology - Research from the United States and Czech Republic add new data to angiology body of knowledge
Aspergillosis - Recent findings from the United States and Italy illuminate research in aspergillosis
Atherosclerosis - Reports from Turkey, the United States and Austria describe recent advances in atherosclerosis research
Biomedical Engineering - Findings from the United States advance knowledge in biomedical engineering research
Biomedical Engineering - New findings from Germany, Japan and the People's Republic of China in the area of biomedical engineering detailed
Biomedical Engineering - New research from France, Japan and the United States in the area of biomedical engineering detailed
Biomedical Engineering - Recent studies from Italy and the United Kingdom add new data to biomedical engineering research
Biomedical Engineering - Reports from the United States and Republic of Korea add new data to biomedical engineering research
Biomedical Engineering - Research from Japan and Singapore add new data to biomedical engineering body of knowledge
Biomedical Engineering - Researchers from the People's Republic of China, Netherlands and Italy publish new studies and findings in the area of biomedical engineering
Biomedical Engineering - Researchers from the United States, France and Portugal detail new studies and findings in the area of biomedical engineering
Biomedical Engineering - Researchers' findings from Japan and the United States advance biomedical engineering research
Biomedical Engineering - Studies from Israel, Japan and the United Kingdom advance knowledge in biomedical engineering research
Cancer Treatment - Recent findings in cancer treatment described by researchers from the United States, Japan and Canada
Cancer Treatment - Researchers from the United States and South Korea publish new studies and findings in the area of cancer treatment
Cardiology - Researchers' findings from Japan, the United States and Taiwan advance cardiology research
Cell Biology - New findings from Austria, the United States and Germany in the area of cell biology detailed
Cell Biology - New findings from the United States in the area of cell biology described
Cell Biology - New findings in cell biology described from Singapore and the United States
Cell Biology - Recent studies from Austria, the United Kingdom and Denmark add new data to cell biology research
Cell Biology - Reports from Japan and Taiwan add new data to cell biology research
Cell Biology - Research from Japan and the United States add new data to cell biology body of knowledge
Cell Biology - Researchers from Australia, Japan and China describe findings in cell biology studies
Cell Biology - Researchers' work from the United States and South Korea adds to cell biology body of knowledge
Diabetes - Research from the United States add new data to diabetes body of knowledge
Diagnostics - Reports from Germany and Netherlands describe recent advances in diagnostics research
Genetics - Data from Israel and the United States advance knowledge in genetics research
Hemangioendothelioma - Recent studies from Germany and the United States add new data to hemangioendothelioma research
Hepatitis B Virus - Findings from Germany, the United States and Japan in hepatitis B virus provide new insights
Hepatitis B Virus - New findings in hepatitis B virus described from Turkey, the People's Republic of China and Spain
Hepatitis C Virus - New findings from the United States and Poland in the area of hepatitis C virus detailed
Imaging - New research from the United States and Japan in the area of imaging detailed
Imaging - Studies from Germany, Netherlands and Italy advance knowledge in imaging research
Leukemia - New findings from Brazil, the United Kingdom and the United States in the area of leukemia described
Leukemia - Researchers from the People's Republic of China and Germany report recent findings in leukemia
Leukemia - Studies from the United States, Italy and Canada describe new findings in leukemia research
Lung Cancer - Researchers from North Ireland, Japan and Italy publish new studies and findings in the area of lung cancer
Ovarian Cancer - Researchers' data from the United Kingdom and Austria advance ovarian cancer research
Transplants - Recent studies from Turkey and the United States add new data to transplants research
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