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Stem Cell Research

Pluripotent spermatogonial stem cells isolated from adult testis

Published in Blood Weekly, July 6th, 2006

Pluripotent spermatogonial stem cells have been isolated from adult testis.

"Embryonic germ cells as well as germline stem cells from neonatal mouse testis are pluripotent and have differentiation potential similar to embryonic stem cells, suggesting that the germline lineage may retain the ability to generate pluripotent cells.

"However, until now there has been no evidence for the pluripotency and plasticity of adult spermatogonial stem cells (SSCs), which are responsible for maintaining spermatogenesis throughout life in the male," researchers in Germany report.

According to K. Guan and colleagues at the University of...

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