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Tissue Engineering

TGF-beta 1 immobilized tri-co-polymer developed for articular cartilage tissue engineering

Published in Blood Weekly, July 6th, 2006

A TGF-beta 1 immobilized tri-co-polymer was developed for articular cartilage tissue engineering.

According to a study from Taiwan, "Tri-co-polymer with composition of gelatin, hyaluronic acid and chondroitin-6-sulfate has been used to mimic the cartilage extracellular matrix as scaffold for cartilage tissue engineering.

"In this study, we try to immobilize TGF-beta 1 onto the surface of the tri-co-polymer sponge to suppress the undesired differentiation during the cartilage growth in vitro."

"The scaffold was synthesized with a pore size in a range of 300-500 mcm. TGF-beta 1 was immobilized on the surface of the tri-co-polymer...

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