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Embryogenesis

Alginate-extracellular matrix gels investigate ovarian follicle development

Published in Blood Weekly, July 6th, 2006

Alginate-extracellular matrix gels are used to investigate ovarian follicle development.

"The extracellular matrix (ECM) provides a 3-dimensional structure that promotes and regulates cell adhesion and provides signals that direct the cellular processes leading to tissue development.

"In this report, synthetic matrices that present defined ECM components were employed to investigate these signaling effects on tissue formation using ovarian follicle maturation as a model system," scientists in the United States report.

According to P.K. Kreeger and colleagues at Northwestern University in Evanston, "In vitro systems for follicle...

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