Published in Blood Weekly, July 13th, 2006
Study 1: Retinoic acid is required early during adult neurogenesis in the dentate gyrus.
"Retinoic acid (RA) is commonly used in vitro to differentiate stem cell populations including adult neural stem cells into neurons; however, the in vivo function of RA during adult neurogenesis remains largely unexplored.
"We found that depletion of RA in adult mice leads to significantly decreased neuronal differentiation within the granular cell layer of the dentate gyrus," scientists writing in the journal Proceedings of the National Academy of Sciences of...
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