Published in Blood Weekly, July 13th, 2006
Study 1: The current hypothesis concerning late allograft failure involves cumulative damage to the kidney.
According to recent review in the journal Transplantation, "The paradigm that chronic rejection causes all progressive late allograft failure has been replaced by a hypothesis of cumulative damage, where a series of time-dependent immune and nonimmune mechanisms injure the kidney and lead to chronic interstitial fibrosis and tubular atrophy, representing a final common pathway of injury and its consequent fibrotic healing response. Allograft...
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Source: Blood Weekly (2006-07-13)
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