Colorectal Cancer
Immunohistochemistry detects mismatch repair gene defects in colorectal cancer
Published in Blood Weekly, July 13th, 2006
"The clinical management of colorectal malignancies that arise via the mismatch repair gene pathway may differ from those that arise from the more common loss of heterozygosity pathway.
"They respond differently to chemotherapy, have a different prognosis and are associated with a raised incidence of metachronous lesions if a germline mutation is present," wrote scientists in the journal Colorectal Disease.
According to the authors, "Established methods of detecting mismatch repair gene defects require the testing for microsatellite instability....
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2006-07-13)
More Articles from Blood Weekly
- Blood Banking
Autologous whole blood may not need to be discarded after prolonged filtration - Blood Banking
Immunomagnetic separation technologies compared for T cell depletion from buffy coats - Genetics & Genomics
Increased cardiovascular risk is associated with tissue plasminogen activator haplotypes - Acute Myeloid Leukemia
Acute myeloid leukemia managed on outpatient basis - Allergy & Immunology
Platelets target dendritic cell differentiation and production of proinflammatory cytokines - Angiology
CABG patency may be assessed with a magnetic resonance spin echo sequence - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
