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Embryonic Stem Cell Research

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors

Published in Blood Weekly, July 13th, 2006

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors.

According to a study from the United States, "Membrane-derived vesicles (MV) are released from the surface of activated eucaryotic cells and exert pleiotropic effects on surrounding cells.

"Since the maintenance of pluripotency and undifferentiated propagation of embryonic stem (ES) cells in vitro requires tight cell to cell contacts and effective intercellular signaling, we hypothesize that MV derived from ES cells (ES-MV) express stem cell-specific molecules that may also support self-renewal and expansion of adult stem cells."

"To address this...

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