Published in Blood Weekly, July 13th, 2006
According to a recent review from South Korea, "Huntington's disease (HD) is a fatal, genetically based late-onset neurodegenerative disorder in which a loss of neostriatal neurons is a main characteristic.
"The CAG trinucleotide repeat expansion encoding polyglutamine tract induces progressive deficits in intra- and intercellular signaling, and subsequent clinical signs developed with aging process."
"CAG-induced neurodegeneration and disease-onset shows aging-dependent pattern. Proposed mechanism of neurodegeneration...
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