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Stem Cell Transplantation

Allo-SCT using cord blood or matched-sibling donors comparable in advanced Hodgkin lymphoma

Published in Blood Weekly, July 13th, 2006

Allogeneic stem cell transplantation using umbilical cord blood or matched-sibling donors is comparable in adults with high-risk advanced Hodgkin's lymphoma.

"We compared the safety and efficacy of allogeneic stem cell transplantation (allo-SCT) after reduced-intensity conditioning using either unrelated umbilical cord blood (UCB) donors or matched-sibling donors (MSDs) for 21 adults at high risk with advanced Hodgkin lymphoma (UCB, n=9; MSD, n=12).

"Both groups were comparable except for younger age in the UCB cohort (median, 28 vs. 42 years; p=0.02)," wrote investigators in the United States.

According to N.S. Majhail and...

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