Blood Weekly

Blood Banking - Fresh and stored blood equally effective reversing anemia-induced brain oxygenation deficits

Endocrinology - Insulin and IGF-I are mainly transported across blood-brain barrier by their own systems

Tissue Engineering - 3-dimensional nanofibrous scaffolds control scaffolds for bone tissue engineering

Tissue Engineering - D,L-beta-hydroxybutyrate promotes cell proliferation in cells plated at high density

Transfusion Medicine - Diabetes or impaired glucose not seen in chronically transfused thalassemia major patients

Acute Myeloid Leukemia - Acute myeloid leukemia prognosticated by size of FLT3 internal tandem duplication

Age-Related Macular Degeneration - Age-related macular degeneration is linked to retinal iron accumulation

Allograft Rejection - Inhibitory effects of apoptotic cells on antidonor response treat transplant rejection

Angiology - Postischemic vasculogenesis is a product of caveolin-driven cell mobilization

Antitumor Immunity - Heat shock fusion protein induces both specific and nonspecific antitumor immunity

Blood Clotting - Future of pharmacogenetics in oral anticoagulation therapy is reviewed

Bone Marrow Transplantation -  Pneumocystis carinii infection sensitizes lung to total body irradiation-mediated lung injury

Brain Injury - CXCR2 has a dual role after brain injury

Breast Cancer - Estradiol and TPA exert their effects on TFF1 gene expression by different mechanisms

Breast Cancer Treatment - Doxorubicin plus interleukin-2 chemoimmunotherapy against breast cancer safe and effective

Breast Cancer Vaccine - HER2/neu-derived peptide GP2 promising for use in breast cancer vaccine

Business Update - China Pharma Holdings announces recent product approvals

Business Update - CryoLife receives tissue from 85,000th donor

Business Update - Spectral signs distribution agreement for endotoxin activity assay with Estor, SpA in Italy

Cancer Immunotherapy - IL-21 enhances tumor-specific cytotoxic T lymphocyte induction by anti-DR5 antibody therapy

Cancer Therapy - Cytokine-containing implants at tumor excision sites may stimulate local immune reactivity

Cancer Therapy - Myeloablative alkylator therapy effects on peripheral blood cells clarified

Cardiac Medical Devices - Study shows Boston Scientific's carotid closed cell stent is safer in stroke prevention

Cardiac Regeneration - Bone marrow cells and cardiac stem cells used for cardiac regeneration

Cardiac Transplantation - Tacrolimus with mycophenolate mofetil advantageous in cardiac transplantation

Cardiology - Aortic valve prosthesis requires a minimized implantation technique

Cardiology - Edwards Lifesciences supports new guidelines for management of patients with heart valve disease

Cardiology - Synthetic Blood receives letter to initiate cardiopulmonary bypass surgery trial in Mexico

Cell Transplantation Therapy - Human nucleus pulposus cell line transplantation delays disc degeneration

Chronic Myeloid Leukemia - ChemGenex presents data on Ceflatonin for treating CML patients resistant to Gleevec

Chronic Myeloid Leukemia - Imatinib mesylate treats secondary malignancy with favorable outcome

Collaborations - CeraPedics and BioD announce collaboration agreement for development of orthopedic products

Colon Cancer - Colon carcinoma cells express HCELL as the major E- and L-selectin ligand

Colorectal Cancer Prognosis - MLH1 and MSH2 expression predicts clinical outcome in colorectal cancer stages II and III

Complementary & Alternative Medicine - Patients with low-grade B-cell malignancies responded to oral green tea extracts

Diabetes Control - Blood pressure management often falls behind in patients with diabetes mellitus

Diagnostics - Leukemia cell differentiation involves a novel signaling molecule

Embryogenesis - Embryoid bodies sequentially express genes associated with developing embryo

Embryogenesis - Oog1 interacts with Ras and Ras-signaling proteins during early embryogenesis

Embryonic Stem Cell Research - Chemically defined medium ensures long-term self-renewal embryonic stem cell differentiation

Embryonic Stem Cell Research - Gap junctions modulate apoptosis and colony growth of embryonic stem cells

Embryonic Stem Cell Research - Genetic screen identifies functionally active genes in embryonic stem cells

Finance - BioTime reports 33% decrease in royalty revenue

Finance - Dutton Associates updates its coverage of Clearant, addresses risks of tainted tissue implants

Gene Therapies - Gene therapy studies underway for treatment of inherited hematological disorders

Gene Therapy - Porcine factor VIII achieved from genetically modified bone marrow-derived stem cells

Graft-Versus-Host Disease - Fatal transfusion-associated GVHD from RBCs of donor homozygous for shared HLA haplotype

Hairy Cell Leukemia - Clone-specific PCR assesses minimal residual disease in hairy cell leukemia

Healthcare Costs - Deep vein thrombosis noninvasive diagnostic testing strategies are evaluated

Heart Attack - Hearts injured by myocardial infarction benefit from angiogenesis gene therapy and stem cells

Heart Failure - Study data suggest Aranesp (darbepoetin alfa) may decrease anemia risk related to heart failure

Hematology - Antiplatelet therapy in populations at high risk for atherothrombosis is focus of review

Hematology - ZymoGenetics completes enrollment for phase 3 trial of recombinant human thrombin

Hemophilia Therapy - Adenoviral gene therapy mediates correction of defect in canine hemophilia A model

Hemophilia Therapy - Endothelial-targeted Sleeping Beauty transposon corrected hemophilia A

Hemophilia Therapy - Tailored hemophilia A prophylaxis results in little bleeding and good joint function

Hepatitis C Virus Pathogenesis - Fas ligand responsible for CXCR3 chemokine induction in CD4 cell-dependent liver damage

Hepatocellular Cancer - Liver tumors treated by hepatic arterial chemoembolization

Herpes Virus Therapy & Prostate Cancer - Systemic oncolytic herpes virus therapy treats immunogenic prostate cancer metastatic to lung

Immune Homeostasis - MP-2 involvement in regulatory processes directed to immune homeostasis maintenance

Ischemia - Erythropoietin initiates angiogenesis in ischemic limbs

Kidney Disease - Troponin T does not add mortality predictive power for dialysis patients

Kidney Transplant - New York City's first three-way kidney transplant takes six surgical transplant teams

Kidney Transplantation - Severe diarrhea in renal transplantation often treated with anti-infectives

Large-B-Cell Lymphoma Therapy - Rituximab added to CHOP effective in pediatric good-prognosis diffuse large-B-cell lymphoma

Leukemia - Acute myeloblastic leukemia Flt3 gene promoter inversely related to PU.1 expression

Leukemia - Healthy individuals showed frequent bcl-2/IgH rearrangements

Leukemia - Leukemia apoptosis linked to calcium-dependent upregulation of E4BP4 expression

Leukemia - Leukemia patient survival in high-risk group was shorter compared to low-risk group

Leukemia - Leukemia prognosticated by c-KIT mutations

Leukemia - Myeloid/natural killer cell precursor acute leukemia diagnosis does not require myeloid antigens

Leukemia - Pediatric T cell acute lymphoblastic leukemia linked to expression of Mer

Leukemia Therapy - Approach to managing leukemia in the developing world is presented

Leukemia Therapy - Patients with treatment-resistant leukemia achieve high responses to Tasigna (nilotinib) in first published clinical trial results

Liver Transplantation - Acute cellular rejection rates are lower in recipient-donor pairs

Liver Transplantation - Antifungal prophylaxis disadvantages and advantages compared in liver transplant patients

Liver Transplantation - Post-transplant vaccination protects against hepatitis B virus

Liver Transplantation - Post-transplantation course of hepatitis C is unrelated to calcineurin inhibitor

Liver Transplantation - Postliver transplant biliary strictures treated with endoscopy have excellent outcomes

Liver Transplantation - Transplant patients with HIV-HBV co-infection can be treated for hepatitis B virus

Living-Donor Liver Transplantation - Pulmonary hypertension can develop after living-donor liver transplantation

Lung Cancer - Cancer/germline gene encodes antigen recognized by autologous CTL induced on lung adenocarcinoma