Published in Blood Weekly, July 20th, 2006
"In the subventricular zone of the adult mammalian forebrain, neural stem cells (NSCs) reside and proliferate to generate young neurons. We screened factors that promoted the proliferation of NSCs in vitro by a recently developed proteomics technique, the ProteinChip system," scientists in Japan report.
According to M. Sakaguchi and colleagues at Keio University in Tokyo, "In this screen, we identified a soluble carbohydrate-binding protein, Galectin-1, as a candidate."
"We show herein that Galectin-1 is expressed in a subset of slowly dividing subventricular zone...
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