Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . July 27th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Banking - Automated cell separators evaluated for cell recoveries from umbilical cord blood units
Medical Devices - Plasma can be separated using a molded microfluidic device
Tissue Engineering - Engineered tissue mimics the acute anterior cruciate ligament
Umbilical Cord Blood Transplantation - Unrelated cord blood transplantation feasible in adults with high-risk malignancy
Angiology - Carotid angioplasty using a membrane stent may reduce the embolic load
Angiology - Carotid artery stenting should be accompanied by a dual antiplatelet regime
Antisense Technology - Transferrin receptor-targeted liposome efficiently delivers antisense DNA
Apoptosis - Leukemia cell-induced apoptosis is sensitized by MEK1 inhibition
Biomedical Engineering - Orthovita receives U.S. FDA approval to market Vitagel surgical hemostat
Blood Safety - Bacterial culturing of platelets more cost-effective than pathogen reduction
Blood Safety - Leukodepletion filters reduce Leishmania in blood products
Burns - Haemophilus influenzae contributes to morbidity but not mortality in burn patients
Business Update - Cepheid expands real-time thermal cycler patent license agreement to include HIV and HCV
Business Update - Cepheid launches CE Mark-certified Smart CMV in vitro diagnostic test for SmartCycler platform
Business Update - CoTherix licenses exclusive rights to develop and commercialize oral and inhaled Fasudil
Business Update - Daxor announces signed agreement from Cabrini Medical Center of Manhattan
Business Update - Daxor announces Yale-New Haven Hospital acquires Blood Volume Analyzer BVA-100
Business Update - Escalon and PointCare Technologies Inc. sign manufacturing, distribution and co-marketing agreement
Business Update - Masimo ranked 7th overall in medical device industry on 2006 Patent Scorecard list
Business Update - MedMira hires marketing consultant, adds sales people in Europe, Middle East, Latin America
Cancer Gene Therapy - Apoptotic susceptibility endowed by induced expression of a fusion gene
Cancer Risk Factors - Epilepsy not considered as a cancer risk factor
Candida Drug Resistance - Candida glabrata cross-resistant between older azole drugs and voriconazole
Cardiac Medical Devices - U.S. FDA approves Abiomed's IDE for IMPELLA 5.0 minimally invasive cardiac support systems
Cardiology - Aprotinin affects downregulation of endogenous thrombin generation
Cardiology - Cardiac output continuous measurements with changing hemodynamics are studied
Cardiology - In adjunctive treatment of ST-segment elevation MI, low-molecular-weight heparin is preferable
Cardiology - Left ventricular assist device weaning method discussed
Cardiology - Left ventricular assist system thrombosis is studied in vivo
Cardiology - Starr-Edwards mitral disk valve prosthesis durable for at least 23 years
Cardiovascular Disease - Prosthetic valve thrombosis etiology was linked to subtherapeutic anticoagulation level
Cartilage Repair - Scaffold containing TGF-beta 1-loaded microspheres induces mesenchymal stem cell differentiation
Cell Biology - Bone marrow-derived mesenchymal cells require angiogenic proteins to affect new vessel growth
Chemotherapy & Anemia - NeoRecormon shows correction of anemia in cancer patients undergoing chemotherapy
Chronic Myeloid Disorders - Chronic myeloid disorders linked to infrequent C-terminal nucleophosmin mutations
Dental Research - Maxillary sinus augmentation lacks significant benefit from platelet-rich plasma
Developmental Biology - Zinc finger gene functions in erythroid and megakaryocytic differentiation
Diabetes Complications - Diabetic microvascular dysfunction can lead to macroangiopathy and microangiopathy
Diabetes Complications - High pulse pressure linked to higher mortality in hypertensive type 2 diabetes
Diabetes Control - Multiple daily insulin shows best glycemic control in diabetes with large blood glucose swings
Diabetes Control - Stochastic model assesses variability of blood glucose time series in diabetes self-monitoring
Diagnostics - Diagnostic Chemicals introduces total bilirubin reagent
Dialysis - Lactate buffer increases peritoneal dialysis-related angiogenesis in the peritoneum
Drug Safety - PGXL Laboratories provides DNA testing for Warfarin patients
Embryonic Neural Stem Cell Research - Embryonic neural stem cells are critically influenced by glucocorticoids
Embryonic Stem Cell Research - Embryonic stem cells induced to differentiate into thyroid follicular cells
Esophageal Cancer - Esophageal cancer survival improved with epoetin alfa after chemoradiation
Finance - Lifeblood Medical raises $1.2 million in series B round of funding
Finance - Regenerative medicine company Tengion Inc. completes $50 million series B financing round
Generic Drugs - U.S. FDA grants approval to market generic form of simvastatin tablets for high cholesterol
Genetics & Genomics - Gene expression molecular signature identified in chronic myeloid leukemia
Graft-Versus-Leukemia - Graft-versus-leukemia effect demonstrated in patients treated for chronic myelomonocytic leukemia
Hand Surgery - Anticoagulation therapy in microsurgery is reviewed
Heart Attack - Cardiac remodeling after myocardial infarction is prevented by erythropoietin
Heart Disease - Bioprosthetic heart valve scaffolds containing stem cells may treat injured hearts
Heart Transplant - Cardiac allograft rejection may be marked by increased serum hyaluronan
Heart Transplant - Cardiac allograft survival prolonged by gene transfer of interleukin-17 receptor
Heart Transplant - Cardiac transplant recipients present changes in lymphatic endothelium
Hematology - Increased rate of bleeding at low platelet counts occurred despite therapy
Hemophilia A - Researchers find a key to a permanent genetic cure for hemophilia A patients
Hemostasis - Enrollment in Phase III clinical trial for OMRIX's thrombin stand-alone product completed
Hepatitis B Therapy - European Commission grants approval for Baraclude (entecavir) for treatment of chronic hepatitis B
Hepatitis B Virus Vaccine - High thymopentin doses improves hepatitis B vaccine seroresponse rate in dialysis patients
Hepatitis C Virus - Recovery from hepatitis C involves virus-specific memory T cells
Hepatocellular Cancer - Waiting list removal rates among patients with nonmalignant and hepatocellular cancer analyzed
Human Papillomavirus & Tobacco Use - Smoking may influence long-term cancer risk by perturbing early immune response to HPV16
Human Papillomavirus Vaccine - Human papillomavirus vaccine immunogenic and antiangiogenic
Hypertension - InterCure introduces RESPeRATE Duo to track personalized blood pressure of two users
Leukemia - B cell chronic lymphocytic leukemia response to nutlin-3 should be studied
Leukemia - Childhood lymphoid malignancies protected against by breast-feeding of more than 6 months
Leukemia - Dasatinib studied in patients with leukemia and resistance or intolerance to imatinib
Leukemia - Hyperleukocytic acute myeloid leukemia (AML) pathogenesis linked to ICAM-1 and LFA-1
Leukemia - Leukemia developed in patient with primary thrombocythemia and absence of BCR/ABL rearrangement
Leukemia - Leukemia patients experienced DNA hypomethylation after 5-aza-2'-deoxycytidine therapy at low doses
Leukemia - Survival of transformed lymphocytes requires human T-cell leukemia virus gene
Liver Transplants - Researchers' finding may cut future need for liver transplants
Lymphoma - Pediatric diffuse large B-cell lymphoma differs from adult type
Medical Devices - Cardiac surgery blood filters for leukocyte and fat removal compared
Medical Devices - Centrifugal blood pump inner flow field model finds areas of high shear stress
Medical Devices - LVAD-associated pathogenesis of microembolization investigated
Medical Devices - Undulation pump-left ventricle assist devices may disturb microcirculation
Melanoma - Mast cells in melanoma samples congregate near vessel tissues
Mergers & Acquisitions - Walgreen Co. to acquire Medmark Specialty Pharmacy Solutions for undisclosed sum
Methemoglobinemia Outbreaks - Methemoglobinemia outbreak occurred among rubber molding workers
Myeloma - Revlimid (lenalidomide) survival data evaluated in previously treated multiple myeloma
Neonatology - Ligation of the right common carotid artery does not result in quantitative EEG changes
Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma risk linked to cytokine polymorphisms in the Tb1/Th2 pathway
Organ Donation - DMV and Donate Life California Organ & Tissue Donor Registry team up to challenge Californians
Organ Transplant - Pharming receives orphan drug designations for rhC1INH from U.S. FDA
Orthopedics - Achilles tendon reconstruction improves as bone marrow cells augment biologic scaffolds
Peripheral Vascular Disease - Cytokines boost the kinetics of bone marrow cell differentiation in ischemic limbs
Personnel - Chemokine Therapeutics names Guy Ely, MD, as chief medical officer
Personnel - Victoria Diaz Cummock appointed to American Red Cross National Board of Governors
Pneumonia - Pneumococcal pneumonia-associated lung coagulation is activated by a tissue factor pathway
Progenitor Cells - Hematopoietic progenitor cell impairment involves down-modulation
Proteomics - Epstein-Barr virus nuclear antigen 2 induces Fc-receptor homolog 5 expression through CBF1 protein
Sickle Cell Anemia - Patients with sickle cell disease exhibit elevated levels of angiogenic protein
Sickle Cell Anemia - Sickle cell disease in Germany was the focus of investigation
Sports Medicine - Blood doping laboratory testing parameter should be changed to hemoglobin concentration
Stem Cell Banking - Environmental monitoring in stem cell banks minimizes contamination risk
Stem Cell Research - Bone marrow-derived keratinocytes not detected in normal skin
Stem Cell Research - Different stem cell treatments both produce results for two similar patients in China
Stem Cell Research - Homocysteine accelerates senescence and reduces proliferation of endothelial progenitor cells
Stem Cell Research - Monocytic leukemia zinc-finger protein is essential for hematopoietic stem cell maintenance
Stem Cell Research - Murine embryos harbor mesenchymal cells with leukocyte and lymphendothelial characteristics
Stem Cell Research - National Children's Leukemia Foundation endorses Missouri Stem Cell Research and Cures Initiative
Stem Cell Research - Notch controls stem cell proliferation and differentiation in dose-dependent manner
Stem Cell Research - Simple animal model used to study epithelial cell differentiation from stem cells
Stem Cell Research - Wnt signals guide embryonic stem cells in developing vessels
Stem Cell Therapy - Cell-based therapy for heart failure is still in the infancy stage
Stem Cell Transplantation - Bone marrow-derived stem cells reverse genetic kidney disease in Alport syndrome
Stem Cell Transplantation - CB transplantation plus coinfusion of mobilized stem cells improve hematopoietic recovery
Stem Cell Transplantation - Early lymphocyte recovery predicts longer survival after stem cell transplantation
Stem Cell Transplantation - EBV-specific T cell reconstitution manages viral reactivation after stem cell transplantation
Stem Cell Transplantation - Echocardiographic imaging documents transplanted adult stem cells in ischemic myocardium
Stem Cell Transplantation - Imatinib alone probably does not cure relapsed CML after hematopoietic stem cell transplant
Stem Cell Transplantation - Mesenchymal stem cells are susceptible to human herpesviruses
Stem Cell Transplantation - Stem cell transplantation timing from last chemotherapy affects lymphocyte collection
Stem Cell Transplantation - TNFd and IL-10 polymorphisms correlate with mortality in unrelated HCST
Stroke - Focal cerebral ischemia models display hypoxia-mediated protein interactions
Thrombopoiesis - NIP-004 is nonpeptidyl c-Mpl activator that stimulates megakaryopoiesis and thrombopoiesis
Type 1 Diabetes - Run-to-run control of blood glucose in type 1 diabetes proves to be a robust model
Aneurysm - New data from Japan, France and the United States lluminates research in aneurysm
Angiology - Data from the United States and Poland advance knowledge in angiology research
Angiology - Findings from Germany, Sweden and Switzerland advance knowledge in angiology research
Angiology - New research from the United States and Germany in the area of angiology detailed
Angiology - Reports from Italy, Canada and the United States describe recent advances in angiology research
Bacterium - Recent findings from Japan, Taiwan and Germany illuminate research in bacterium
Biomedical Engineering - New research from France, Italy and Japan in the area of biomedical engineering detailed
Biomedical Engineering - Recent findings from Italy, Germany and Canada illuminate research in biomedical engineering
Blood Banks - Researchers' work from the United States and Australia adds to blood banks body of knowledge
Breast Cancer - New findings from the United States, Germany and Greece in the area of breast cancer detailed
Breast Cancer - Studies from Sweden, the United States and the South Korea add new findings to breast cancer body of knowledge
Cancer Research - Researchers' data from the United States, People's Republic of China and Austria advance cancer research
Cancer Treatment - Findings from Spain and the United States describe new data in cancer treatment research
Cardiology - Reports from Germany and the United States describe recent advances in cardiology research
Cell Biology - Findings from South Korea and United Kingdom describe new data in cell biology research
Cell Biology - Recent studies from the United States, Japan and Taiwan add new data to cell biology research
Cell Biology - Researchers from the United States describe findings in cell biology studies
Diagnostics - Research from Germany and Netherlands in diagnostics provides new insights
Genetics - Findings from the United States and Iceland describe new data in genetics research
Genetics - Research from the United States and Japan add new data to genetics body of knowledge
Genetics - Studies from Japan and Sweden add new findings to genetics body of knowledge
Heart Attack - Research from the United States and Japan add new data to heart attack body of knowledge
Heart Attack - Studies from the United States add new findings to heart attack body of knowledge
Heart Disease - Data from the United States, Switzerland and Poland advance knowledge in heart disease research
Heart Disease - Findings from Spain, Italy and Canada in heart disease provide new insights
Hematology - New findings from Scotland, the United Kingdom and Israel in the area of hematology described
Hematology - New findings in hematology described from Taiwan, Sweden and the United States
Hepatitis B Virus - Researchers from Germany, Taiwan and Turkey report details of new studies and findings in the area of hepatitis B virus
Hepatitis C Virus - New data from Sweden, Canada and Germany lluminates research in hepatitis C virus
Herpes - Reports from Denmark and the United States advance knowledge in herpes research
Imaging - Findings from Switzerland and Germany describe new data in imaging research
Imaging - Studies from the United States, Finland and Taiwan advance knowledge in imaging research
Leukemia - Data from the United States, Canada and United Kingdom advance knowledge in leukemia research
Leukemia - Findings from Italy and the United States in leukemia provide new insights
Leukemia - New findings in leukemia described from the United States, Italy and Spain
Leukemia - Researchers from the United States, Japan and Italy report recent findings in leukemia
Lung Cancer - Findings from Belgium, the United States and Japan in lung cancer provide new insights
Neurology - Studies from the United States and Sweden add new findings to neurology body of knowledge
Neurology - Studies from the United States, United Kingdom and Japan advance knowledge in neurology research
Obesity - New findings in obesity described from Israel, the United States and Italy
Transplants - New findings in transplants described from France and the United States
Transplants - Reports from Canada, Australia and the United Kingdom advance knowledge in transplants research
Transplants - Reports from Japan, Germany and the United States describe recent advances in transplants research
Transplants - Research from Brazil, Turkey and Germany in transplants provides new insights
Transplants - Studies from Germany, Turkey and the United States describe new findings in transplants research
Transplants - Studies from Japan and the United States add new findings to transplants body of knowledge
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