Heart Disease
Bioprosthetic heart valve scaffolds containing stem cells may treat injured hearts
Published in Blood Weekly, July 27th, 2006
"Human mesenchymal stem cells (MSCs) differentiate into multiple cell-lineages and may serve as an alternative source of seed cells for tissue engineering. We investigated whether MSCs could be induced to differentiate into endothelial cells (ECs) and function as seed cells for the in vitro construction of tissue-engineered heart valves (TEHVs)," researchers in the People's Republic of China report.
"Aortic or pulmonary valve homografts were decellularized with 0.1% sodium dodecylsulphate and used as scaffolds for TEHVs. The MSCs were isolated from human bone marrow...
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Source: Blood Weekly (2006-07-27)
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