Tissue Engineering
Bone implant pretreatment with cyclic RGD-peptides enhances osteointegration
Published in Blood Weekly, August 10th, 2006
According to a study from Germany, "In tissue engineering, the application of biofunctional compounds on biomaterials such as integrin binding RGD-peptides has gained growing interest. Anchorage-dependent cells like osteoblasts bind to these peptides thus ameliorating the integration of a synthetic implant.
"In case sterilized bone grafts are used as substitutes for reconstruction of bone defects, the ingrowth of the implanted bone is often disturbed because of severe pretreatment such as irradiation or autoclaving, impairing the biological and mechanical...
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Source: Blood Weekly (2006-08-10)
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