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Pediatric Stem Cell Transplantation

Cidofovir safe and effective for adenoviral infection in pediatric stem cell transplantation

Published in Blood Weekly, August 10th, 2006

Cidofovir is safe and effective for the treatment of adenoviral infection in pediatric stem cell transplantation patients.

"Adenovirus (ADV) infections are associated with significant morbidity and mortality after hematopoietic stem cell transplantation (HSCT). The virus is endemic in the general pediatric population and frequently causes severe disease in immunocompromised patients, especially children," scientists in the United States report.

According to the authors, "We report our experience with cidofovir (CDV) for treatment of ADV infection in 57 HSCT patients, median age 8 years (range 0.5-26). Peripheral blood was prospectively screened...

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