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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . August 17th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Artificial Liver - Solution preserves urea cycle enzymes in hepatocytes

Cardiovascular Research - Endotoxic shock-associated hemodynamics may be improved with large-pore membrane hemofiltration

Developmental Biology - Growth and osteogenic differentiation of bone marrow stromal cells characterized

Tissue Engineering - Skin preserved long-term in anhydric sodium chloride resumes function after transplantation

Alzheimer Disease - Exelon Patch, first transdermal therapy for Alzheimer disease, may provide new treatment approach

Angiology - Femoral arterial occlusive disease successfully treated with Hemobahn/Viabahn endoprostheses

Angiology - Right gastroepiploic artery grafts demonstrate increased blood flow

Anticancer Therapy - Interleukin-18 inhibits osteosarcoma metastasis partly via cell mobility suppression

Antitumor Immunity - Glucocorticoid-induced TNF receptor family related gene activation enhances antitumor immunity

Antitumor Therapy - Human-mouse chimeric antibody against transferrin receptor has a strong antitumor effect

Apoptosis - Tumor necrosis factor-related apoptosis-inducing ligand inhibits tumor growth

Atherosclerosis - Arteriosclerotic nanoplaque formation was the aim of femtosecond dynamics study

Autoimmune Disease - Rigel's Janus Kinase 3 (JAK3) inhibitors extend allograft survival in organ transplant model

Biomedical Engineering - Ventricular assist device 3-D numerical model of flow is developed

Breast Cancer - Lymphatic mapping enables real-time intraoperative detection of lymphatic metastases

Business & Finance - HemoBioTech announces conversion of class A warrants

Business Update - Cord Blood America announces it is nearing collection of adipose tissue stem cells for future use

Business Update - Dade Behring launches tacrolimus test on its Dimension, V-Twin, and Viva-E Systems

Business Update - University of Texas Medical Branch purchases Sysmex' hematology testing lab equipment

Cancer Immunotherapy - Cancers could be treated by targeting endothelial-cell growth factor-1

Cancer Therapy - Angiogenesis clarified in a human neuroblastoma xenograft model

Cancer Therapy - Thiazolidinedione-derived novel therapeutic agents proposed for cancer therapy

Cardiac Medical Devices - Data compares clinical indicators of Cypher Sirolimus-Eluting Coronary Stents to bare metal stents

Cardiac Medical Devices - Merit Medical receives CE mark to market U.S. FDA-approved Impress catheter in Europe

Cardiac Medical Devices - Spectranetics enrolls first patient in trial of laser ablation device in arterial blockage

Cardiology - Centrifugal blood pump-associated hemolysis is numerically predicted

Cardiology - Left ventricular mechanical support with an intravascular microaxial blood pump is assessed

Cardiovascular Disease - Inflammatory cytokine gene polymorphisms may modulate myocardial infarction prognosis

Chronic Myeloid Leukemia - Cases of chronic myelogenous leukemia and rheumatic disease linked

Chronic Myeloid Leukemia - Leukemia response to dasatinib evaluated

Chuvash Polycythemia - Patients with Chuvash polycythemia bear high levels of angiogenic cytokines

Clinical Trials - U.S. FDA cancels meeting on proposed clinical trial for blood substitute product

Cryopreservation - Vitrification methods increase efficiency of long-term stem cell storage

Dental Care - HemCon launches dental dressing using same technology as other HemCon dressings

Diabetes Therapy - NaCS/PDADMAC is well suited for microencapsulation of pancreatic beta cells

Diagnostics - Circulating tumor cells in peripheral blood monitored in gastric cancer patients

Diagnostics - New rapid species identification test helps physicians identify infection sooner

Drug Development - Characterization and development of AMN107 discussed

Drug Development - Positive results reported from animal studies of chronic treatment for high cholesterol

Drug Resistance - Patients treated with enoxaparin before CABG showed heparin resistance intra-operatively

Embryonic Stem Cell Research - Embryonic stem cell electroporation enhances small and macromolecule loading efficiency

Embryonic Stem Cell Research - Embryonic stem cells generate insulin-secreting cells

Enzymology - Antiangiogenic polypeptide relies on permissive matrix proteins to generate apoptosis

Finance - Cryo-Cell International reports second quarter 2006 results

Fitness & Wellness - Exercise training improves fibrinolytic potential and TNF-alpha expression after fatty meal

Gastric Cancer - Cancer and Leukemia Group B Gastrointestinal Cancer Committee efforts reviewed

Gene Research - Sporadic cancer linked to disruption of FANCC and FANCG

Generic Drugs - Teva announces tentative U.S. FDA approval of generic version of Lotrel for hypertension

Genetics & Genomics - Targets of aberrant hypermethylation identified in myeloid leukemia

Graft-versus-Host Disease - Endothelial cell-derived microparticles elevated in acute graft-versus-host disease

Graft-versus-Host Disease - RDP58 does not prevent graft-versus-host disease

HIV/AIDS Diagnostics - Calypte's Aware BSP HIV-1/2 Rapid Test approved for addition to USAID waiver list

HIV/AIDS Therapy - Etanercept does not appear to increase morbidity or mortality rates in HIV/AIDS

Hair Development - miRNA-processing enzyme dicer essential for hair follicle morphogenesis and maintenance

Heart Transplantation - Cardiac allograft rejection is associated with endothelin converting enzyme-1 upregulation in host liver

Heart Transplantation - Neutrophil transendothelial migration potential predicts rejection severity in heart transplant

Heart Transplantation - Rat cardiac transplants show beneficial effects from alpha-tocopheryl succinate

Hematology - Abbott receives U.S. FDA clearance for Cell-Dyn Ruby hematology instrument

Hematology - Coagulation and atherothrombotic disease are the focus of review

Hematology - Heparin-induced thrombocytopenia is prevalent in patients receiving mechanical circulatory support

Hemophilia - Bayer HealthCare introduces product trial program for Kogenate FS with Bio-Set

Hepatitis B Virus - Abbott receives U.S. FDA approval for automated blood screening tests for hepatitis B

Hepatitis C Virus - Hepatitis C viral isolates from blood donors genotyped

Hepatocellular Carcinoma - Response of hepatocellular cancer to transcatheter arterial chemoembolization reviewed

Immunotherapy - Radiation induces successful antitumor immunotherapy

Internal Bleeding - Philips leads development project for ultrasound device to stem bleeding on the battlefield

Kaposi Sarcoma - AIDS-related Kaposi sarcoma lesions give way to antiangiogenic interleukin-12

Kidney Development - Multiple genes provide a link between kidney progenitor cells

Kidney Disease - Renal allograft dysfunction associated with increased arterial stiffness

Kidney Transplantation - Exogenous retrovirus activation not detected in renal allograft rejection

Kidney Transplantation - National trial gives support for steroid withdrawal in kidney transplants

Kidney Transplantation - Renal replacement therapy can treat suspected or confirmed inborn errors of metabolism

Leukemia - Concise history of the Cancer and Leukemia Group B reviewed

Leukemia - Endogenous human promyelocytic leukemia isoforms characterized

Leukemia - Leukemia chemotherapy outcome predicted by manganese superoxide dismutase polymorphism

Leukemia - Leukemia linked to downregulation of DBC1 expression

Leukemia - Murine leukemia virus particles activate Rac1 in HeLa cells

Leukemia - Origins of the Cancer and Leukemia Group B Cancer Control and Health Outcomes Committee recounted

Leukemia - Transient leukemia in neonates with Down syndrome characterized

Lung Cancer - Free radical formation by cigarette smoke generates DNA double-strand breaks

Market Analysis - Concomitant with new drug launches from 2009 onwards, HCV market estimated to double by 2010

Melanoma - Melanoma disease status might benefit from composite molecular assessment of blood

Molecular Biology - Endoglin depends on key regulatory factors during angiogenesis

Multiple Myeloma - Myeloma treated by histone deacetylase inhibitor LBH589

Multiple Myeloma - SCID mouse model enables rapid evaluation of treatments for multiple myeloma

Myocardial Infarction - Reperfusion injury pathogenesis is examined with focus on the role of fibrinogen

Neurogenesis - Cortical neurogenesis timing is encoded within lineages of individual progenitor cells

Neurogenesis - Neurogenesis lacking in adult cerebellum after Purkinje cell degeneration

Obstetrics - Delay in cord clamping may help prevent iron deficiency in infants less than 6 months of age

Obstetrics - Increased risk of low birth weight was seen in nonanemic women taking daily iron supplements

Oncology - Peripheral T cell lymphoma treated by autologous transplantation

Parkinson Disease - Activation of p53 signaling initiates apoptotic death in Parkinson disease

Patents - Daxor announces European patent for Max-100 injection kit used with Blood Volume Analyzer BVA-100

Pneumocystis Pneumonia - Alveolar macrophage apoptosis suppression prolongs survival with Pneumocystis pneumonia

Prognostics - Response of brain metastases to Efaproxiral predicted by red blood cell concentration

Raynaud Syndrome - Raynaud syndrome in patients with systemic sclerosis may be improved by atorvastatin

Rectal Cancer - Growth hormone receptor overexpression predicts rectal cancer response to radiotherapy

Stem Cell Research - 5T4 antigen transiently upregulated during early embryonic stem cell differentiation

Stem Cell Research - Bone marrow stem cells prevent remodeling of ischemic heart via paracrine signaling

Stem Cell Research - Cardiac myxoma cells exhibit embryonic endocardial stem cell features

Stem Cell Research - Differentiation-related changes in mitochondrial properties indicate stem cell competence

Stem Cell Research - Multipotent adult stem cells isolated from hair follicles

Stem Cell Research - Neurosphere-derived neurons similar to immature neurons differentiating in vivo

Stem Cell Research - Stem cell factor fused with erythropoietin mimetic peptide expressed in Escherichia coli

Stem Cell Research - Stem cell factor fused with mimetic peptide in Escherichia coli

Stem Cell Research - Stem cells from fat tissue may be new source for smooth muscle cells

Stem Cell Research - Tmtsp is a marker gene for primitive hematopoietic cells and endothelial cells

Stem Cell Transplantation - Adoptive T-cell transfer may protect from adenovirus-related complications

Stem Cell Transplantation - Cord stem cell transplant for primary immunodeficiencies comparable to other stem cell sources

Stem Cell Transplantation - Dual-energy myocardial SPECT monitors transplanted cell distribution in relation to infarction site

Stem Cell Transplantation - Fatigue increased in patients receiving high-dose chemotherapy followed by stem cell transplant

Stem Cell Transplantation - High-dose chemotherapy and stem cell transplant eradicates relapsed primary effusion lymphoma

Stem Cell Transplantation - Mesenchymal stem cell infusion treats therapy-resistant graft-versus-host disease

Stem Cell Transplantation - Refractory cytomegalovirus infection successfully treated after stem cell transplant

Stem Cell Transplantation - Stem cell transplant postremission improves high-risk acute lymphoblastic leukemia survival

Surgical Technology - Blood avoidance program gives families surgical options

Tissue Engineering - 3-D scaffold plus nonviral gene carrier enhances mesenchymal stem cell DNA expression

Tissue Engineering - Mesenchymal stem cell adhesion to PLGA scaffolds via type-I collagen fosters osteogenesis

Tissue Engineering - Perivenous fibrin glue application enhances saphenous vein graft thickening

Transplant Medicine - Mycophenolate mofetil decreases risk of late acute liver transplant rejection

Transplant Medicine - Y's Therapeutics compound for graft dysfunction granted orphan status in U.S. and Europe

Umbilical Cord Blood Transplantation - Early-onset thyrotoxicosis occurs after cord blood transplant in acute myelogenous leukemia

Von Willebrand Disease - Lentiviral vectors expressing von Willebrand factor correct endothelial cells

Angiology - Recent findings from Germany, Japan and the United States illuminate research in angiology

Angiology - Researchers from Sweden, Italy and Scotland describe findings in angiology studies

Angiology - Researchers' findings from Germany and the United States advance angiology research

Apoptosis - Findings from Italy, Spain and the United States in apoptosis provide new insights

Apoptosis - Research from the United States, Australia and Scotland in apoptosis provides new insights

Atherosclerosis - Recent findings in atherosclerosis described by researchers from the People's Republic of China, Austria and United States

Biomedical Engineering - New data from Finland and the United States lluminates research in biomedical engineering

Biomedical Engineering - Recent findings in biomedical engineering described by researchers from the United Kingdom, South Korea and Canada

Biomedical Engineering - Reports from Japan, Finland and Scotland advance knowledge in biomedical engineering research

Biomedical Engineering - Researchers from Japan, Portugal and the South Korea report details of new studies and findings in the area of biomedical engineering

Biomedical Engineering - Researchers from the People's Republic of China, Italy and Taiwan provide details of new studies and findings in the area of biomedical engineering

Biomedical Engineering - Studies from Germany describe new findings in biomedical engineering research

Cancer Treatment - Research from Germany, Netherlands and Egypt add new data to cancer treatment body of knowledge

Cancer Treatment - Research from Netherlands, United States and France in cancer treatment provides new insights

Cancer Treatment - Researchers' work from the United Kingdom, United States and Japan adds to cancer treatment body of knowledge

Cardiology - New research from the United States in the area of cardiology detailed

Cardiology - Recent findings from the United States and Greece illuminate research in cardiology

Cardiology - Reports from Italy and the United States advance knowledge in cardiology research

Cardiology - Reports from Japan, Spain and the United States advance knowledge in cardiology research

Cardiology - Researchers from the United States and France publish new studies and findings in the area of cardiology

Cardiology - Researchers' findings from Italy, Germany and Finland advance cardiology research

Cardiology - Studies from Germany, the United States and Japan advance knowledge in cardiology research

Cell Biology - Findings from India, Germany and the South Korea in cell biology provide new insights

Cell Biology - Reports from Switzerland and Belgium add new data to cell biology research

Cell Biology - Research from France and the United States in cell biology provides new insights

Cell Biology - Researchers from France and the United States publish new studies and findings in the area of cell biology

Cell Biology - Researchers from Italy and the United Kingdom detail new studies and findings in the area of cell biology

Cervical Cancer - New data from the United States, South Korea and United Kingdom lluminates research in cervical cancer

Cord Blood - Studies from the United States advance knowledge in cord blood research

Diabetes - New findings in diabetes described from Canada and Switzerland

Diabetes - Recent studies from South Korea and Japan add new data to diabetes research

Diabetes - Researchers' data from the United States and South Africa advance diabetes research

Heart Attack - New findings from Australia, Japan and the Republic of Korea in the area of heart attack detailed

Heart Disease - Studies from the United States, Taiwan and United Kingdom advance knowledge in heart disease research

Hematology - Findings from the United States and Germany describe new data in hematology research

Hematology - Studies from the United States, Turkey and Netherlands describe new findings in hematology research

Hepatitis C Virus - Researchers from Norway, Germany and the United States report details of new studies and findings in the area of hepatitis C virus

Hepatocellular Carcinoma - Recent findings from the United States and Greece illuminate research in hepatocellular carcinoma

Herpes - Research from the United States add new data to herpes body of knowledge

Leukemia - New research from France, Denmark and Brazil in the area of leukemia detailed

Leukemia - Recent studies from the United States, Italy and Germany add new data to leukemia research

Leukemia - Research from Germany and Sweden add new data to leukemia body of knowledge

Leukemia - Studies from the United States add new findings to leukemia body of knowledge

Obesity - Findings from Austria, Spain and the United States advance knowledge in obesity research

Oncology - New findings in oncology described from the United States

Ovarian Cancer - Researchers from the United Kingdom and Austria report recent findings in ovarian cancer

Proteins - Recent findings in proteins described by researchers from the United States

Respiratory System - Findings from the United States and Brazil advance knowledge in respiratory system research

Stroke - Recent findings in stroke described by researchers from France, Sweden and Taiwan

Transplants - New findings from Germany, Japan and the United States in the area of transplants described

Transplants - Recent findings in transplants described by researchers from Italy, the United States and Spain

Transplants - Researchers from Japan, the United States and France detail new studies and findings in the area of transplants

Transplants - Researchers' findings from Turkey and France advance transplants research

Transplants - Researchers' work from Taiwan, the United States and France adds to transplants body of knowledge

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