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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . August 24th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Banking - Transfused blood storage duration is associated with morbidity and mortality

Bone Marrow - Tumor growth impeded natural-killer-cell maturation

Cell Biology - Bone marrow stromal cell differentiation into mature osteoblasts is limited by osterix interference

Critical Care Medicine - Erythropoiesis abnormalities contribute to early-onset anemia in septic shock

Tissue Engineering - Cryopreserved vascular umbilical cord cells used to engineer viable heart valves

Acute Myeloid Leukemia - Acute myeloid leukemia risk-adapted therapy discussed

Adverse Drug Reaction - Toxicity of combination therapy detected in cirrhotic patients with hepatitis C

Angiology - Heparin-induced thrombocytopenia after cardiac surgery results in high mortality

Angiology - Varicocele treatment depends on knowledge of anatomic variants

Angiology - Venous thrombosis risk increased by hemostatic protein nonsense polymorphism

Blood Transfusion - Allogeneic blood requirement after knee replacement surgery is reduced

Business & Finance - Haemonetics reports first-quarter revenues of $111 million

Business & Finance - HemoSense Q3 revenue up 86%, marking 14th consecutive quarter of double-digit growth

Business Update - Celera receives approval to CE Mark its new RealTime PCR HCV genotyping test

Business Update - Dade Behring introduces BCS XP System, coagulation analyzer for the high-volume laboratory

Business Update - Dade Behring introduces infectious disease testing instrument, the Quadriga BeFree System

Business Update - DomaniCell launches hospital-based cord blood banking business

Business Update - Medwave, maker of blood-pressure devices, contracts with Tri-anim

Business Update - Span-America Medical Systems signs agreement with Novation to offer Secure I.V. system

Cell Therapy - Functional thymus formation initiated by postnatal epithelial progenitor cell

Diabetes Control - Solvay submits fenofibrate/metformin fixed-dose combination product for E.U. approval

Diabetes Control - Study finds 1 in 5 youths with diabetes has 2 or more risk factors for early heart disease

Diagnostics - HemoCue presents new point-of-care test for total white blood cell count

Diagnostics - Non-invasive liver fibrosis biomarkers revealed in hepatitis C hemophiliacs

Embryonic Stem Cell Research - Embryonic stem cell maintenance and cryopreservation efficacy protocols established

Enzymology - Puromycin insensitive leucyl-specific aminopeptidase ordains the development of biological systems

Epilepsy - Ketogenic diet monitoring is possible using subcutaneous microdialysis

Erythropoiesis - Expression balance paces erythroid differentiation

Finance - Cord Blood America expects second quarter revenues could set record

Finance - Dade Behring reports 5% revenue growth in second quarter, earnings per share increases 139%

Finance - Diomed Holdings signs $10 million equity financing

Finance - ExonHit Therapeutics announces first-half 2006 revenues up 46%

Finance - Immucor announces record fiscal fourth quarter revenues of $50M

Finance - Medical equipment maker Span-America reports Q3 2006 sales up 18% over prior year

Gene Research - Acute lymphoblastic leukemia not linked to transcription factor PU.1 mutations

Graft-versus-Host Disease - Multiple activation molecules preferentially upregulated on CD4+ and CD8+ T cells in GvHD

Graft-versus-Host Disease - Severe acute graft-versus-host disease-related costs and survival rates increasing

HIV/AIDS Pathogenesis - HIV protease cleaves poly(A)-binding protein

Heart Disease - Cardiac angiogenesis may be compromised by the effects of continuous nitroglycerin therapy

Hematology - Sickle red cell adhesion and vaso-occlusion in the microcirculation are inhibited by antioxidants

Hemophilia Therapy - Adeno-associated virus delivering factor VIII provides multiyear benefit in hemophilia A

Hodgkin Lymphoma - Hodgkin lymphoma patients did not benefit more from radiotherapy than consolidation chemotherapy

Hypertension - Aldosterone/renin ratio as a hypertension screening test is reviewed

Infectious Diseases - Mortality can be reduced in systemic inflammatory response syndrome and sepsis

Information Technology - Information Data Management releases Prelude 1.2, a blood donor management system

Information Technology - Roche launches Web site for organ transplantation community

Ischemia - NO-synthase induction affects cardioprotection of modified endotoxine diphosphoryl lipid A

Kidney Transplant Medicine - Large transplant study shows CellCept based drug combination is best immunosuppressant

Leukemia - Adult T cell leukemia apoptosis induced by survivin overexpression and sodium arsenite

Leukemia - Children with leukemia in a second remission treated by HLA-matched sibling transplantation

Leukemia - Infants with acute lymphoblastic leukemia and a germline MLL gene cured by chemotherapy alone

Leukemia - Leukemia patients' loss of tumor protein 53 resulted from absence of chromosome 17 p-arm

Leukemia - TAL1 oncoprotein modulates NF-kB1 expression in a subset of human T cell leukemia cells

Licensing Agreements - Nostrum obtains licensing rights from IMTECH for clinical development of therapeutic protein

Lipoproteins - Alcohol use, vascular disease, and lipid-lowering drugs are considered in review

Liver Disease - Liver failure patients are supported with a molecular adsorbent recirculating system

MALT Lymphoma - MALT lymphoma-associated translocations not linked to nuclear BCL-10 expression

Mesothelioma & Pneumonitis - Fatal pneumonitis was linked to intensity-modulated radiation therapy for mesothelioma

Multiple Myeloma - July issue of Journal of Medicinal Chemistry highlights Infinity's lead oncology drug candidate

Neurogenesis - Increased transforming growth factor-beta 1 inhibited hippocampal neurogenesis in aged mice

Osteochondroma - Benign osteosarcoma distinguished from pediatric osteochondroma by plasma proteomic signature

Pancreatic Cancer - Pancreatic cancer extended resection techniques and indications discussed

Pancreatic Islet Cell Transplantation - Study explores hemoglobin-based oxygen carrier in pancreatic islet cell transplantation

Parkinson Disease - Embryonic stem cell-derived neurons in Parkinson disease exhibit delayed neuronal death

Renal Cancer - Renal cancer patients treated by nephrectomy have medium-term survival

Sepsis Research - Patient unresponsiveness in sepsis may involve blocked transcription

Stem Cell Research - Adult liver cells have enormous plasticity and differentiation potential

Stem Cell Research - Bone marrow stem cells transdifferentiate into male germ cells

Stem Cell Research - Bone marrow-derived mesenchymal stem cells express nestin when expanded on particular glass

Stem Cell Research - D2-40 antibody immunoreactivity detected in neural stem cells

Stem Cell Research - Embryonic stem cell self-renewal occurs in the absence of DNA methyltransferases

Stem Cell Research - Epigenetic modifications in osteogenic differentiation modeled

Stem Cell Research - Fetal liver hepatic progenitor cells express the oval cell marker Thy-1

Stem Cell Research - Free cord blood stem cell storage program offers treatment option for high-risk babies

Stem Cell Research - Intrinsic characteristics of embryonic stem cells and their microenvironment regulate their fate

Stem Cell Research - Maturation-resistant dendritic cells unable to induce tolerance to allogeneic stem cells

Stem Cell Research - Mesenchymal stem cells reside in virtually all postnatal organs and tissues

Stem Cell Research - Non-nuclear transfer-based approaches reprogram differentiated cells into multipotent cells

Stem Cell Research - Osteoclasts degrade endosteal components and promote hematopoietic progenitor cell mobilization

Stem Cell Research - P19 progenitor cells progress to organized contracting myocytes after stimulation

Stem Cell Research - Post-translational control is a regulatory factor in primary hematopoietic stem cells

Stem Cell Research - Putative stem cells are localized near the edge of the mammary anlagen

Stem Cell Research - Retinoblastoma protein is not required for self-renewal and multilineage differentiation

Stem Cell Transplantation - Neonatal skin-derived precursors generate functional neural progeny

Stem Cell Transplantation - ViaCell completes phase 1 trial of potential therapy for stem cell transplant candidates

Stroke - Carotid artery stenting deemed safe treatment option for elderly in recent study

Surgical Technology - Major hepatectomy in children approached via blood transfusion-free method

Tissue Engineering - Embryonic stem cell-derived cardiomyocytes contract on 3D collagen scaffold

Tissue Engineering - Myoblast construct increases regenerated muscle with minimal scar formation in tongue

Tissue Engineering - Stem cell chemotaxis improved when cocultured with smooth muscle cells

Tissue Engineering - Suspension bioreactor scales up neural precursor cell aggregate production

Angiology - Findings from Germany, Switzerland and Canada describe new data in angiology research

Angiology - Recent findings from the United States illuminate research in angiology

Angiology - Research from Japan and the United States add new data to angiology body of knowledge

Angiology - Researchers' data from Belgium, the United States and the People's Republic of China advance angiology research

Biomedical Engineering - New findings from Taiwan, Italy and the People's Republic of China in the area of biomedical engineering described

Biomedical Engineering - Reports from the United States advance knowledge in biomedical engineering research

Cardiology - Data from Italy, the United States and Denmark advance knowledge in cardiology research

Cardiology - Findings from the United States and Greece in cardiology provide new insights

Cardiology - New data from Canada and the United States lluminates research in cardiology

Cell Biology - Findings from the United States, NORTH Ireland and South Korea describe new data in cell biology research

Cell Biology - Recent findings from the United States, Japan and Taiwan illuminate research in cell biology

Cell Biology - Recent findings in cell biology described by researchers from South Korea and Italy

Cell Biology - Researchers' data from the United States, United Kingdom and Germany advance cell biology research

Cord Blood - New findings from Australia, the United States and Japan in the area of cord blood detailed

Cord Blood - New research from the United States and Netherlands in the area of cord blood detailed

Dental Research - Studies from Germany and Finland add new findings to dental body of knowledge

Diabetes - Findings from the United States, Taiwan and Australia in diabetes provide new insights

Diabetes - Recent findings from the United States and Sweden illuminate research in diabetes

Diabetes - Recent findings from the United States, Canada and France illuminate research in diabetes

Diabetes - Recent findings in diabetes described by researchers from South Korea and Germany

Diabetes - Reports from Netherlands, France and United States add new data to diabetes research

Genetics - Recent findings in genetics described by researchers from the United States and Canada

HIV/AIDS - Studies from Brazil, Sweden and Zimbabwe add new findings to HIV/AIDS body of knowledge

Heart Attack - Findings from the United States and Italy describe new data in heart attack research

Heart Attack - Studies from the United Kingdom, Australia and United States add new findings to heart attack body of knowledge

Hepatitis C Virus - New research from the United States, Spain and Israel in the area of hepatitis C virus detailed

Herpes - Findings from Denmark and the United States advance knowledge in herpes research

Leukemia - Findings from Germany and Sweden describe new data in leukemia research

Leukemia - Findings from Italy, the United States and Netherlands in leukemia provide new insights

Leukemia - New findings from the United Kingdom and United States in the area of leukemia described

Leukemia - Recent findings in leukemia described by researchers from the United States and Italy

Leukemia - Recent studies from Germany, the United States and Japan add new data to leukemia research

Leukemia - Research from the United States, South Korea and People's Republic of China in leukemia provides new insights

Leukemia - Researchers from the United States and United Kingdom report recent findings in leukemia

Leukemia - Researchers' data from Denmark, Italy and Germany advance leukemia research

Leukemia - Studies from the United States and Germany advance knowledge in leukemia research

Lung Cancer - Reports from Belgium and Japan advance knowledge in lung cancer research

Myeloma - Researchers from Japan, the United States and Italy describe findings in myeloma studies

Neurology - Findings from the United States, United Kingdom and Japan advance knowledge in neurology research

Neurology - Research from the United States, Japan and People's Republic of China add new data to neurology body of knowledge

Neurology - Studies from the United States, Israel and Netherlands add new findings to neurology body of knowledge

Obesity - New findings from Denmark, the United Kingdom and the United States in the area of obesity detailed

Oncology - Studies from Japan and the United States add new findings to oncology body of knowledge

Pneumonia - New findings in pneumonia described from Netherlands and South Africa

Transplants - Findings from Switzerland, France and Germany in transplants provide new insights

Transplants - New data from the United States, Italy and Japan lluminates research in transplants

Transplants - New findings from Japan, the United States and the United Kingdom in the area of transplants described

Transplants - Research from Switzerland, Japan and France in transplants provides new insights

Vaccines - Studies from the United States and People's Republic of China advance knowledge in vaccines research

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