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Tissue Engineering

Artificial extracellular matrix mimics ECM topography in native tissue

Published in Blood Weekly, September 7th, 2006

An artificial extracellular matrix mimics ECM topography in native tissue.

"In order to mimic in vivo topography of the native tissue created by extracellular matrix (ECM) components, which make up all soft tissues, the surface features of each biomaterial should be considered as a nano-dimensional structure.

"In this study, an artificial ECM was designed to mimic the nanostructured topography created by ECM components in native tissue," scientists in Japan report.

According to the authors, "The proliferation and differentiation of mesenchymal stem cells (MSCs) was investigated in a 3-dimensional (3-D) network of nanofibers formed...

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