Leukemia

Leukemia favorable outcome predicted by simplified flow cytometric assay

Published in Blood Weekly, September 7th, 2006

A simplified flow cytometric assay was developed that could identify a high proportion of children with acute lymphoblastic leukemia (ALL) who would have an excellent early treatment response and a high likelihood of cure.

According to recent research published in the journal Blood, "Bone marrow normal lymphoid progenitors (CD19+, CD10+, and/or CD34+) are exquisitely sensitive to corticosteroids and other antileukemic drugs. We hypothesized that, in patients with B-lineage ALL, cells with this phenotype detected early in treatment should be leukemic rather than normal."

"We therefore developed a simple and inexpensive flow cytometric assay for...

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Source: Blood Weekly (2006-09-07)

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