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Tissue Engineering

Living autologous heart valves engineered from prenatally harvested progenitors

Published in Blood Weekly, September 14th, 2006

Living autologous heart valves have been engineered from prenatally harvested progenitors.

According to recently published research from Switzerland, "Heart valve tissue engineering is a promising strategy to overcome the lack of autologous growing replacements, particularly for the repair of congenital malformations. Here, we present a novel concept using human prenatal progenitor cells as new and exclusive cell source to generate autologous implants ready for use at birth."

"Human fetal mesenchymal progenitors were isolated from routinely sampled prenatal chorionic villus specimens and expanded in vitro. A portion was cryopreserved. After...

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