Published in Blood Weekly, September 21st, 2006
According to recent research from England, "MLL fusion genes are a predominant feature of acute leukemias in infants and in secondary acute myeloid leukemia (AML) associated with prior chemotherapy with topo-II poisons. The former is considered to possibly arise in utero via transplacental chemical exposure."
"A striking feature of these leukemias is their malignancy and remarkably brief latencies implying the rapid acquisition of any necessary additional mutations," explained M. Eguchi and colleagues, Institute of Cancer Research. "We have suggested that these coupled features might be explained...
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