Published in Blood Weekly, September 28th, 2006
"Earlier it was reported that metabolic arrest followed by incubation at 4 degrees C reduces the PLT storage defect. Here it is reported that this treatment also reduces binding and phagocytosis by macrophages," scientists writing in the journal Transfusion report.
"Phagocytosis of mepacrine-labeled PLTs by macrophages changes the latter into bright fluorescent particles easily detected by fluorescence-activated cell sorting. In combination with conventional binding analysis it was found that binding to phorbol 12-myristate...
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