Stem Cell Transplantation
Preoperative low-dose irradiation promotes long-term allograft acceptance
Published in Blood Weekly, September 28th, 2006
According to recent research published in the journal Transplantation, "A simplified conditioning protocol including single-dose preoperative thymic and low-dose whole body irradiation with or without subsequent donor bone marrow transplantation (BMTx) can be applied in porcine lung transplantation.
"We hypothesized that this protocol would prolong allograft survival. Left-sided single lung transplantation from major histocompatibility complex (MHC)-mismatched donors was performed in 27 minipigs."
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Source: Blood Weekly (2006-09-28)
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