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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . October 5th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Safety - Pall System to detect bacteria in red blood cells granted CE Mark

Blood Safety - Safety concerns over the Canadian blood supply drives patients to autodonate

Blood Safety - Simian foamy virus infection occurred by whole-blood transfer in rhesus macaques

Tissue Engineering - Porous micro-patterned scaffold developed for vascular tissue engineering

Tissue Engineering - Tissue-engineered tooth produced by embryonic tooth germ cells in 3-dimensional scaffold

Alzheimer Disease - Selective Alzheimer Disease Indicator-1 gene abundantly expressed by stem cells

Anemia - Researchers find a relationship between anemia and impaired thinking

Antitumor Therapy - Recurrent gastrointestinal stromal tumors in complete remission after imatinib treatment

Apoptosis - Azidothymidine in adult T cell leukemia/lymphoma patients results in tumor cell death

Apoptosis - Pinusolide evaluated for its antileukemic potential

Artificial Blood - Leech behavior modified following foraging for artificial blood

Atherosclerosis - Links between inflammation and thrombogenicity in atherosclerosis are reviewed

Biosynthesis - Cholesterol biosynthesis disorders are influenced by precursors that alter cell rafts and function

Blood Safety - Antihemophilic factor concentrates are not without risk

Blood Safety - Pathogen safety reconfirmed for Prolastin

Blood Safety - Precautions necessary during hand surgery on patients at high-risk for blood-borne viruses

Breast Cancer - Breast cancer-specific mRNA transcripts after adjuvant chemotherapy predicts poor survival

Business & Finance - Haemacure reports third quarter revenues of $31,409 and updates Hemaseel project

Business Update - Abbott signs deal with American Red Cross for blood screening with four key tests

Business Update - Deltex Medical new trial data show CardioQ reducing duration of hospital stays by one-third

Business Update - Lifeblood Medical establishes Cell Preservation Solutions, LLC as a wholly owned subsidiary

Business Update - Medical Simulation Corporation launches online course on hemodynamic monitoring

Business Update - Tasco Holdings International renamed Bio-Matrix Scientific Group Inc. with new symbol BMSN

Cancer Immunotherapy - FcR gamma expression not required for HeFi-1-mediated tumor growth inhibition

Cancer Marker - p16INK4 overexpression is a reliable marker of HPV-induced oral high-grade squamous dysplasia

Cancer Pharmacogenomics - Genomics used to predict response to chemotherapy

Cancer Therapy - Single-dose pegfilgrastim induces stem cell mobilization in malignant lymphoma or multiple myeloma

Cancer Therapy - Tumor angiogenesis is limited by promyelocytic leukemia tumor suppressor

Cardiac Medical Devices - U.S. FDA approves first totally implanted permanent artificial heart for humanitarian uses

Cardiology - Cardiac effects of enzyme replacement therapy for mucopolysaccharidosis probed

Cardiology - Nuvelo completes enrollment in Phase III trial of alfimeprase in acute arterial occlusion

Cardiology - Published study shows enoxaparin safer than heparin in elective PCI or coronary angioplasty

Cardiovascular Disease - Evaluation, treatment of ischemic cardiac risk before and after renal transplantation are examined

Cardiovascular Research - Researchers examine a drug that can mobilize angiogenic cells in a matter of hours

Cell Transplants - Reduced survival after HLA-identical SCT may be caused by pre-existing viral infections

Cervical Paraganglioma - Cervical paraganglioma-related neurological deficits prevented by early management

Colon Cancer - IL-11-receptor alpha-protein expression decreased in colon carcinoma

Colorectal Cancer - Colorectal cancer treatment with nadroparin was safer than enoxaparin in terms of bleeding risk

Colorectal Cancer - Isolated tumor cell status in regional lymph nodes correlates with colorectal cancer stage

Complementary & Alternative Medicine - Triptolide displayed potent antileukemic activity

Corneal Graft - Corneal graft rejection risk is lowered in rabbits treated with rapamycin implants

Diabetes Complications - Blood flow velocity reduction may raise retinal thickness of macula in diabetic macular edema

Diabetes Research - Transplant treatment approach common to Type 1 Diabetes proves effective for Type 2 Diabetes

Diabetes Therapy - Hyperglycemic impairment is counteracted by benfotiamine

Diagnostics - Arkansas researchers create test for acetaminophen poisoning in children and adults

Drug Development - Animal research results show nutmeg extracts illicit anti-diabetic activity in rats

Drug Development - Ovation and Cardinal Health announce plans to manufacture Panhematin

Embryonic Stem Cell Research - Magnetically labeled embryonic stem cells tracked both in vitro and in vivo

Environmental Health - Cyanobacterial toxins in water supplies should be examined for carcinogenicity

Finance - Dynavax secures equity financing commitment of up to $30 million

Finance - ThermoGenesis Corp. reports Q4 2006 net revenues up 14.8% over year ago to $3,557,000

Gastric Cancer - Oncogenic T-antigen of JC virus is frequently present in gastric cancers

HIV & Venous Thrombotic Events - Venous thrombotic events in HIV patients are due to abnormalities of protein S and factor VIII

Hematology - Anemia raises cardiovascular disease risk in patients with elevated serum creatinine

Hematology - Long-term intensive plasmapheresis donors can safely donate 850 ml plasma up to 60 times/yr

Hematology - New tool helps blood specialists improve patient care

Hematopoiesis - Cytokines induce megakaryocytopoiesis and thrombopoiesis from X-irradiated stem cells

Hemophilia - Pediatric hemophilia quality of life outcomes assessed by CHO-KLAT

Hepatitis C Virus - Chronic hepatitis C virus may involve hepatic progenitor cells

Hepatitis C Virus - Hepatitis C virus-positive liver transplant patients may not benefit from treatment withdrawal

Hepatitis C Virus - Iron accumulation in hepatitis C is influenced by Helicobacter pylori

Immunomodulator - Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation

Invasive Aspergillosis Therapy - Antifungal therapy not warranted at initial invasive aspergillosis diagnosis

Kaposi Sarcoma Therapy - Kaposi sarcoma effectively treated with 8 Gy single-dose radiotherapy

Kidney Disease - Experimental glomerulonephritis models benefit from mesenchymal stem cell transplantation

Leukemia - Acute myelogenous leukemia remission should be confirmed by FISH

Leukemia - Leukemia antiproliferation and apoptosis induced by C-glycosides

Leukemia - Leukemia chemotherapy efficacy evaluated by minimal residual disease measurement

Leukemia - Leukemia p53-mediated apoptosis induced by Mdm2 inhibitor Nutlin-3a

Leukemia - Leukemia prognosticated by ZAP-70 protein expression

Leukemia - Leukemia resistance to glucocorticoid not related to inability to up-regulate glucocorticoid receptor expression

Leukemia - Leukemia response to chemotherapy predicted by CASP8AP2 expression

Leukemia - Leukemia risk in children with Down syndrome linked to household chemical exposure

Leukemia - Pediatric leukemia treated by home-based chemotherapy might be feasible

Leukemia - T cell acute lymphoblastic leukemia/lymphoma target identified

Liver Disease - Toray, JT, Torii agree to co-develop antipruritus drug for hepatic disease patients in Japan

Lung Cancer - Herbal mixture downregulates COX-2 nonsmall cell lung cancer cells

Lung Cancer - Lung cancer response and progression predicted by D-dimer plasma levels

Malaria - Pasteur Institute scientists report discovery of malaria parasite

Melanoma - Melanoma growth and metastasis increase with excess placenta growth factor expression

Mergers & Acquisitions - CyGenics acquires stake in DNAPro in exchange for Cell Sciences subsidiary

Multiple Myeloma - Multiple myeloma is linked to differential vascular endothelial growth factor expression

Myelofibrosis - Chronic idiopathic myelofibrosis aberrant collagenase expression clarified

Myocardial Infarction - Post-heart attack cardiac repair requires CD18 recruitment of endothelial cells

Neonatal Leukemia Treatments - Treatment outcomes improved in neonatal leukemia in Japan

Occupational Exposure - Cancer morbidity possibly linked to iron and steel workers in Korea

Oncology - Acute myeloid leukemia and myelodysplastic syndrome find new target of 11q amplification in GAB2

Osteogenesis - Osteogenesis at titanium implant/bone marrow interface under masticatory loading evaluated

Ovarian Cancer - Ovarian carcinoma cells vary in sensitivity to various chemotherapy agents

Pain Management - Computer program may improve pain relief for sickle cell patients

Personnel - HemoSense increases role for Executive VP Timothy I. Still

Personnel - HemoSense names Gordon Sangster as CFO

Personnel - Immucor names Dr. Gioacchino De Chirico as CEO, replacing Edward L. Gallup

Personnel - Verax Biomedical names James Lousararian as chief executive officer

Pertussis Toxin - Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells

Progenitor Cells - Hyperglycemia accelerated EPC senescence by p38 mitogen-activated protein kinase activation

Proteomics - Thyroid hormone stimulates cardiomyocyte protein synthesis via p70(S6K) pathway activation

Pulmonary Arterial Hypertension - Lung association and Myogen to partner on pulmonary arterial hypertension awareness campaign

Pulmonary Hypertension - Evolving dilemmas in portopulmonary hypertension management are considered

Sickle Cell Anemia - Sickle cell zinc inversely correlates with adhesion molecule concentration

Solid Tumors - Pediatric solid tumors tolerated depsipeptide well

Spermatogenesis -  Drosophila gene wh with WD40 repeats essential for spermatogenesis

Stem Cell Collection - Stem cell apheresis prediction method generates accurate and immediate yield predictions

Stem Cell Mobilization - CD34+ yields do not decline in second half compared with first half of apheresis

Stem Cell Mobilization - Rapid succession of peripheral blood progenitor cell mobilization cycles is described

Stem Cell Research - Aggrecan constitutively expressed by MSC and type X collagen expressed as an early event

Stem Cell Research - BMSCs cells may be primary target cell for estrogen in maintaining bone formation

Stem Cell Research - GRP78 essential for embryonic cell growth and pluripotent cell survival

Stem Cell Research - Leukemia inhibitory factor induces proliferation and self-renewal of embryonic stem cells

Stem Cell Research - p38 MAPK regulate dental pulp cell alkaline phosphatase activity

Stem Cell Research - Proposed acquisition will give Genzyme a complementary late-stage transplant product

Stem Cell Transplantation - Bacteria-contaminated grafts rarely result in unfavorable clinical outcomes

Stem Cell Transplantation - Factors related to spermatogenesis in long-term survivors after stem cell transplantation determined

Stem Cell Transplantation - High risk of poor health-related quality of life in children prior to stem cell transplantation

Stem Cell Transplantation - High-dose chemotherapy and stem cell transplant feasible in myeloma and AL amyloidosis

Stem Cell Transplantation - Pretransplantation factors predict for treatment-related myelodysplastic syndrome after SCT

Stroke - Blood pressure monitoring during first 24 hours of acute ischemic stroke may prevent complications

Tissue Engineering - Cardiomyocyte sheet electrical coupling occurs rapidly via functional gap junction formation

Tissue Engineering - Controlled modifications to cell substrate influence mesenchymal stem cell differentiation

Tissue Engineering - Vitronectin and collagen I differentially regulate osteogenesis in mesenchymal stem cells

Type 1 Diabetes - Type 1 diabetes models show neovascular improvement with reactive oxygen species control

Aneurysm - Researchers from Japan, France and Germany describe findings in aneurysm studies

Angiology - New findings from Spain, India and Italy in the area of angiology described

Angiology - Research from Germany, Japan and lawtonj@msnotes in angiology provides new insights

Apoptosis - Studies from the United States and Ireland advance knowledge in apoptosis research

Biomedical Engineering - Recent findings from the People's Republic of China, Italy and United States illuminate research in biomedical engineering

Biomedical Engineering - Research from Netherlands, Germany and United Kingdom in biomedical engineering provides new insights

Biomedical Engineering - Researchers from Germany and Ireland detail new studies and findings in the area of biomedical engineering

Biomedical Engineering - Researchers' work from Belgium, Finland and the United Kingdom adds to biomedical engineering body of knowledge

Cancer Research - Recent findings from the United States, Singapore and Finland illuminate research in cancer

Cancer Treatment - New data from the United States and Sweden lluminates research in cancer treatment

Cancer Treatment - Recent findings from the United States illuminate research in cancer treatment

Cancer Treatment - Reports from the People's Republic of China, Japan and United States add new data to cancer treatment research

Cancer Treatment - Researchers from Netherlands, United States and Germany report details of new studies and findings in the area of cancer treatment

Cardiology - Data from Italy, Taiwan and Japan advance knowledge in cardiology research

Cardiology - Recent findings from the United States and Japan illuminate research in cardiology

Cardiology - Research from Japan, Germany and the United States in cardiology provides new insights

Cell Biology - Findings from Scotland, Australia and Japan advance knowledge in cell biology research

Cell Biology - Findings from the United States and Finland describe new data in cell biology research

Cell Biology - New findings in cell biology described from the United States and South Korea

Cell Biology - Recent findings from South Korea and United Kingdom illuminate research in cell biology

Cell Biology - Researchers from Brazil, France and Spain detail new studies and findings in the area of cell biology

Cell Biology - Researchers from Spain and Japan report details of new studies and findings in the area of cell biology

Cell Biology - Researchers' data from Germany advance cell biology research

Cell Biology - Studies from Canada and Japan advance knowledge in cell biology research

Cell Biology - Studies from Germany, Sweden and the United States add new findings to cell biology body of knowledge

Diabetes - New findings from the United States, Netherlands and Japan in the area of diabetes described

Diabetes - Recent studies from Austria, France and the United States add new data to diabetes research

Diabetes - Researchers from Denmark and the United States report recent findings in diabetes

Diabetes - Researchers from the United States and Ireland report recent findings in diabetes

Diabetes - Researchers from the United States and Sweden report details of new studies and findings in the area of diabetes

Diabetes - Researchers from the United States, Canada and Wales detail new studies and findings in the area of diabetes

Heart Attack - New findings in heart attack described from Germany, Denmark and Netherlands

Heart Attack - Researchers' findings from Japan and Greece advance heart attack research

Heart Disease - Recent findings from Canada, Japan and the United States illuminate research in heart disease

Hematology - Researchers from the United States, Belgium and Spain report details of new studies and findings in the area of hematology

Hematology - Researchers from Turkey and the United States publish new studies and findings in the area of hematology

Hepatocellular Carcinoma - New findings from Taiwan and Japan in the area of hepatocellular carcinoma detailed

Leukemia - Findings from the United States and Canada in leukemia provide new insights

Leukemia - New findings in leukemia described from Germany and the United Kingdom

Leukemia - Recent findings from the United States and Scotland illuminate research in leukemia

Leukemia - Reports from Japan, the United Kingdom and France describe recent advances in leukemia research

Leukemia - Researchers from Germany describe findings in leukemia studies

Leukemia - Researchers from the United Kingdom, Turkey and United States publish new studies and findings in the area of leukemia

Lymphoma - Researchers from Finland, Denmark and the Saudi Arabia provide details of new studies and findings in the area of lymphoma

Lymphoma - Studies from the United States and Switzerland advance knowledge in lymphoma research

Melanoma - Reports from the United States advance knowledge in melanoma research

Neurology - Findings from France, Italy and Sweden advance knowledge in neurology research

Neurology - Recent findings in neurology described by researchers from Japan, Brazil and the United States

Neurology - Researchers from Italy, the United States and Sweden describe findings in neurology studies

Neurology - Studies from the United States describe new findings in neurology research

Papillomavirus - New data from France, Finland and the People's Republic of China lluminates research in papillomavirus

Peripheral Vascular Disease - Reports from Germany, the People's Republic of China and the United Kingdom advance knowledge in peripheral vascular disease research

Transplants - New findings in transplants described from Canada, Belgium and Germany

Transplants - New research from Switzerland and the United States in the area of transplants detailed

Transplants - Recent findings from the United States, Turkey and Germany illuminate research in transplants

Transplants - Reports from the United States and Italy describe recent advances in transplants research

Transplants - Researchers from Ireland, U and France detail new studies and findings in the area of transplants

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