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Atherosclerosis



Links between inflammation and thrombogenicity in atherosclerosis are reviewed



October 5th, 2006

Links between inflammation and thrombogenicity in atherosclerosis are reviewed.

According to recent research from the United States, "Plaque disruption and subsequent thrombus formation play a critical role in the clinical manifestations of atherothrombosis. Vulnerable lesions are characterized by the existence of core rich in lipid, macrophages and tissue factor (TF)."

J.F. Viles-Gonzalez and colleagues working with the Mount Sinai School of Medicine summarized, "Plaque disruption facilitates the interaction between flowing blood with the inner components (TF) of disrupted atherosclerotic lesions triggering the coagulation cascade. TF, thrombin,...


Source: Blood Weekly (2006-10-05)

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