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Heart Attack

Researchers' findings from Japan and Greece advance heart attack research

Published in Blood Weekly, October 5th, 2006

Investigators in Japan and Greece have published new heart attack data.

Study 1: Canine myocardial infarction (MI) models show erythropoietin (EPO) enhances cardiac tissue neovascularization.

According to recent research from Japan, "We investigated the effects of EPO on neovascularization and cardiac function after MI. Erythropoietin exerts antiapoptotic effects and mobilizes endothelial progenitor cells (EPCs)."

"We intravenously administered EPO (1,000 IU/kg) immediately [EPO(0) group], 6 h [EPO(6 h) group], or 1 week [EPO(1 wk) group] after the permanent ligation of the coronary artery in dogs. Control animals received saline...

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