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Cancer Marker
p16INK4 overexpression is a reliable marker of HPV-induced oral high-grade squamous dysplasia
October 5th, 2006
p16INK4 overexpression is a reliable marker of human papillomavirus-induced oral high-grade squamous dysplasia. According to a recently published report from the United States, "Human papillomavirus (HPV) infection has been implicated in the development of high-grade squamous dysplasia and carcinoma of the oral cavity in the absence of other known risk factors such as smoking. "HPV-induced oral dysplasia or carcinoma may be a unique tumor entity in terms of biologic behavior and treatment decisions. In detecting such cases, most reported studies have used techniques that are less sensitive than DNA amplification." "Recent reports...
Source: Blood Weekly (2006-10-05)
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