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Cardiovascular Research



Researchers examine a drug that can mobilize angiogenic cells in a matter of hours



October 5th, 2006

To speed healing at sites of injury - such as heart muscle after a heart attack or brain tissue after a stroke - doctors would like to be able to hasten the formation of new blood vessels. One promising approach is to "mobilize" patients' blood vessel-forming cells, called angiogenic cells, so these cells can reach the injured area.

Recently, researchers at Washington University School of Medicine in St. Louis demonstrated that a drug called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours instead of days, as was the case with a related agent called G-CSF.

Angiogenic cells reside mainly in the bone marrow,...


Source: Blood Weekly (2006-10-05)

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