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Gastric Cancer
Oncogenic T-antigen of JC virus is frequently present in gastric cancers
October 5th, 2006
Oncogenic T-antigen of JC virus is present frequently in gastric cancers. "JC virus (JCV) is a polyomavirus that commonly infects humans and is the causative agent of progressive multifocal leukoencephalopathy in immune-compromised patients. "An association between JCV and human cancers long has been suspected, because this virus induces brain tumors in several animal models," investigators in the United States report. According to scientists, "The oncogenic potential of JCV is mediated by a transforming protein, the T-antigen (T-Ag), which is a multifunctional protein that transforms cells through interactions with various...
Source: Blood Weekly (2006-10-05)
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