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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . October 12th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Banking - Autologous blood transfusion storage condition effects are studied

Blood Safety - Cerus initiates Phase I clinical trial for Intercept blood system for red blood cells

Kidney Research - Study reveals that white blood cells can both hurt and help transplanted kidneys

Needlestick Injuries - Majority of needlestick injuries can be prevented

Anesthesia - Sevoflurane effects on cytokines in patients undergoing CABG are investigated

Angiology - Aggressive anticoagulation is not indicated for coronary artery bypass graft surgery

Angiology - Cardiopulmonary bypass circuit alterations do not improve platelet function

Anthrax - Life Therapeutics to provide antianthrax plasma for hyperimmune development

Antifungals - Combination antifungal therapy valuable in pre-emptive management of high-risk patients

Blood Banking - New York Blood Center experiencing blood shortage

Blood Clotting - Study showing superior safety profile of Lovenox versus heparin in PCI patients published

Blood Safety - U.S. FDA fines American Red Cross $4.2 million for failure to meet established blood safety laws

Bone Marrow Transplantation - Veto cells may be used for tolerance induction without graft-versus-host disease

Business & Finance - ThermoGenesis reports Q4 2006 net revenues of $3,557,000 up from $3,099,000 a year ago

Business Update - Curis announces new cancer programs, formation of China-based subsidiary

Business Update - CyGenics to focus on tissue and cord blood banking

Business Update - Hospice Pharmacia reports increased demand for pharma care services in inpatient units

Cancer Gene Therapy - Gene therapy model reveals unique risk factors for insertional mutagenesis

Cancer Incidence - Cancer incidence among pesticide applicators not related to cyanazine exposure

Cancer Risk Factors - Innate immune inflammation against Helicobacter hepaticus induces mammary adenocarcinoma

Cardiomyopathy - Doxorubicin-induced cardiomyopathy is limited by erythropoietin

Cardiovascular Health - Aerobic endurance training lowers blood pressure by reducing systemic vascular resistance

Cardiovascular Research - New international guidelines for heart transplant candidates standardize patient care

Cervical Cancer Prognostics - NF-kappa B upregulation does not predict high-risk human papillomavirus in cervical cancer

Chronic Gastritis - Dendritic cell immune response to Helicobacter antigen critical to gastritis persistence

Clinical Trials - Human BioSystems to meet with U.S. FDA to discuss platelet human infusion testing

Collaborations - CardioVascular BioTherapeutics announces clinical collaboration

Diabetes Pathogenesis - In prediabetes, soluble P-selectin may not contribute to prothrombotic state or atherogenesis

Down Syndrome - Individuals with Down syndrome have higher leukemia risk but lower solid tumor risk

Drug Development - Patients with solid tumors had manageable toxicity when treated with OSI-7836

Embryonal Brain Tumor - Notch inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

Embryonic Stem Cell Research - Embryonic cell lines not derived directly from paired blastomeres

Environmental Health - Elevated polycyclic aromatic hydrocarbon exposure related to reduced fetal and child growth

Gastric Cancer - Gastric cancer chemosensitivity to anticancer drugs increased by trichostatin A

Gene Research - Leukemic oncogenes identified by phosphoproteomic analysis

Glaucoma - Glaucoma clinical outcomes after valve implantation may be influenced by plate material

HIV/AIDS-Associated Primary Cerebral Lymphoma - HAART exposure not associated with HIV-associated primary cerebral lymphoma

Heart Failure - Anemia, renal dysfunction are common in chronic heart failure outpatients

Hematology - Cardiac mortality in thalassemia major patients is predicted by LV restrictive filling pattern

Hematology - Platelet dysfunction assessed using a novel whole-blood aggregometer

Hematology - Predictors are identified for development of elevated antiheparin/platelet factor 4 antibody titers

Hematology - Rebound platelet activation is linked to cessation of NSAIDs and COX-2 inhibitors

Hematology - Researchers create a roadmap to integrin activation

Hematology - Snake venom anticoagulant proteins are presented in review of structure, function, mechanism

Hypertension - Medicines Company completes clevidipine safety trials, initiates severe hypertension trial

Infectious Diseases - Hospital-acquired infections surveillance model is developed

Infective Endocarditis - gC1qR/p33 blockade reduces Staphylococcus aureus colonization in infective endocarditis

Ischemia - Direct lung ischemia reperfusion injury is regulated by interleukin

Kidney Transplantation - Proteome Sciences evaluates biomarkers of kidney transplant with tandem mass tag technology

Kidney Transplantation - Urinary cytotoxic molecular markers for diagnosing renal transplant acute rejection are tested

Legal Issues - Court rules in favor of Diomed on marked EVLT Sheath, dismisses AngioDynamics' Declaratory Judgment

Leukemia - Adult leukemia managed by sensitive minimal residual disease monitoring

Leukemia - Cell growth arrest induced by AML1-ETO possibly linked to CX43 expression

Leukemia - Chronic lymphocytic leukemia prognosis not affected by familial trait

Leukemia - Human T cell leukemia virus type 1-induced cellular transformation linked to TAX

Leukemia - Leukemia could not be treated by arsenic trioxide

Leukemia - Leukemia patients find new hope in adaphostin therapy

Leukemia - Leukemogenesis promoted by an alternatively spliced protein isoform

Leukemia - Richter's transformation of leukemia to diffuse large cell lymphoma detected by PET/CT

Lung Cancer - Increased macrophage-derived chemokine gene expression linked with lung cancer prognosis

Lung Transplantation - Clinical breakthrough emerges for Steen Solution in lung transplantations

Market Analysis - Hurdles impacting success or failure of 28 leading stem cell companies, focus of report

Medical Devices - Kane biotech begins efficacy study with KBI-4258 coating technology

Microbial Colonization - Impact of gut microbiota composition on cytokine profile development evaluated in children

Multifocal Motor Neuropathy - Refractory multifocal motor neuropathy improves after high-dose cyclophosphamide

Multiple Myeloma Therapy - Thalidomide plus dexamethasone is effective in newly diagnosed multiple myeloma

Myeloma - Multiple myeloma of the cervical spine palliated by external-beam radiation

Natural Products - Cardiovascular events in chronic smokers may be prevented with green tea consumption

Needlestick Injuries - Universal precautions against needle stick injuries lacking in U.K. hospitals

Nontuberculous Mycobacteria - Disseminated nontuberculous mycobacteria emerging in HIV-negative immunosuppressed patients

Ovarian Cancer - Leaf extract induces ovarian cancer cell apoptosis and inhibits tumor growth

Pediatrics - Neurodevelopment inversely related to blood lead levels <10 mcg/dL

Pseudomonas Aeruginosa Outbreaks - Drug-resistant Pseudomonas aeruginosa bacteriemia occurred in hematology patients

Pulmonary Aspergillosis - Cavitation formation predicts time until radiologic remission in invasive pulmonary aspergillosis

Respiratory Medicine - Upgrading donor lung quality will improve organ availability

Scleroderma - Patients with systemic sclerosis harbor bone marrow microenvironment defects

Sickle Cell Anemia - Icagen reports data monitoring committee meeting results in phase III trial of ICA-17043

Sickle Cell Anemia - Sickle cell anemia bacteremia associated with bone morphogenetic protein polymorphisms

Stem Cell Research - A researcher isolates adult stem cells from blood that can develop five types of cells

Stem Cell Research - Corneal stem and progenitor cell markers localized

Stem Cell Research - Cytokines regulate postnatal hematopoietic stem cell expansion

Stem Cell Research - Embryonic stem cell reversible gene expression induced by a RNA vector

Stem Cell Research - Identified peptide selectively binds to embryonic carcinoma stem cells

Stem Cell Research - Interferon-alpha-2b differentiates mesenchymal stem cells into osteoblasts

Stem Cell Research - Mesenchymal stem cell proliferation induced by 8-hydroxyquinoline derivatives

Stem Cell Research - Notch signal inhibition induces myotube hypertrophy via CD34 negative reserve cell recruitment

Stem Cell Research - Sodium butyrate-treated embryonic stem cells yield hepatocyte-like cells with glycolytic phenotype

Stem Cell Research - Stem cells identified from umbilical cord blood with embryonic and hematopoietic traits

Stem Cell Research - Transcriptionally active umbilical cord blood-derived basophils isolated via purification

Stem Cell Therapy - Labeled stem cell PET assesses tissue distribution after intracoronary injection

Stem Cell Transplantation - High-dose chemotherapy and stem cell transplantation controls CNS histiocytic disorders

Stem Cell Transplantation - Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells

Stem Cell Transplantation - Parainfluenza virus type 3 infection highly prevalent after stem cell transplantation

Stem Cell Transplantation - Risk factors identified for post-transplant lymphoproliferative disorder

Stem Cell Transplantation - Transplanted bone marrow-derived stem cells have potential to migrate to cochlea

Thrombosis - Dangerous international normalized ratios in patients receiving warfarin were examined

Tissue Engineering - Clearant presents patient data at one-year post-surgery showing complete range-of-motion recovery

Tissue Engineering - Mathematical model developed for cell growth and diffusion in a porous scaffold

Tissue Engineering - Rabbit cornea substitute constructed with fibrin-agarose scaffold

Transplant Medicine - Non-use of hearts, lungs after consent for donation is examined in Canadian multicenter study

Transplant Medicine - Organ transplantation, organ donation and mental retardation are considered in review

Uterine Cervical Cancer - Dihydrodiol dehydrogenase overexpression associated with papillomavirus in uterine cervical cancer

Angiology - New findings from the United States, Taiwan and United Kingdom in the area of angiology described

Angiology - Reports from Netherlands, United States and Turkey advance knowledge in angiology research

Angiology - Researchers from France, Poland and the New Zealand report recent findings in angiology

Angiology - Researchers from South Korea and United States provide details of new studies and findings in the area of angiology

Angiology - Studies from Sweden, Taiwan and Italy add new findings to angiology body of knowledge

Apoptosis - Researchers' work from Canada, the People's Republic of China and Finland adds to apoptosis body of knowledge

Atherosclerosis - Findings from Japan, Brazil and Netherlands describe new data in atherosclerosis research

Biomedical Engineering - Data from Switzerland, the United States and Netherlands advance knowledge in biomedical engineering research

Biomedical Engineering - Findings from Japan, Italy and the United States in biomedical engineering provide new insights

Cancer Treatment - Researchers from Italy and the United States report recent findings in cancer treatment

Cancer Treatment - Studies from Taiwan, Spain and the United States advance knowledge in cancer treatment research

Cardiology - Researchers from Japan and the United States report details of new studies and findings in the area of cardiology

Cell Biology - Data from Canada, Japan and the United States advance knowledge in cell biology research

Cell Biology - Findings from Italy, Spain and the United States in cell biology provide new insights

Cell Biology - Reports from the United States and People's Republic of China describe recent advances in cell biology research

Cell Biology - Reports from the United States, Japan and NORTH Ireland advance knowledge in cell biology research

Cell Biology - Researchers from Netherlands, United States and Italy describe findings in cell biology studies

Cell Biology - Researchers' findings from Japan and Germany advance cell biology research

Cell Biology - Researchers' work from the United Kingdom, United States and Greece adds to cell biology body of knowledge

Diabetes - Recent findings from Netherlands, France and Italy illuminate research in diabetes

Diabetes - Researchers from the United Kingdom and Sweden provide details of new studies and findings in the area of diabetes

Diabetes - Studies from New Zealand, Finland and Denmark describe new findings in diabetes research

Genetics - Findings from Germany, the United States and the People's Republic of China describe new data in genetics research

HIV/AIDS - Research from Canada, the United Kingdom and Brazil add new data to HIV/AIDS body of knowledge

Hematology - New data from Germany and the United States lluminates research in hematology

Hemophilia - Recent findings from the United States illuminate research in hemophilia

Hepatitis C Virus - Researchers from the United Kingdom, Norway and United States describe findings in hepatitis C virus studies

Herpes - Researchers from Greece, Italy and Japan report details of new studies and findings in the area of herpes

Leukemia - New findings from Germany in the area of leukemia detailed

Leukemia - New research from Japan and Germany in the area of leukemia detailed

Leukemia - Studies from Greece, the United States and France describe new findings in leukemia research

Lymphoma - Researchers from France, Japan and Australia describe findings in lymphoma studies

Neurology - Researchers from the United States provide details of new studies and findings in the area of neurology

Parkinson Disease - Studies from the United States and United Kingdom advance knowledge in Parkinson disease research

Renal Cancer - Researchers' work from the United States, Japan and People's Republic of China adds to renal cancer body of knowledge

Transplants - New data from Spain, Austria and the United States lluminates research in transplants

Transplants - Recent studies from Italy, Sweden and Switzerland add new data to transplants research

Transplants - Research from the People's Republic of China, South Korea and Switzerland add new data to transplants body of knowledge

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