Apoptosis

Researchers' work from Canada, the People's Republic of China and Finland adds to apoptosis body of knowledge

Published in Blood Weekly, October 12th, 2006

Apoptosis data are the focus of recent research from Canada, the People's Republic of China and Finland.

Study 1: A recent study from Canada has reported that the TRAIL apoptotic pathway mediates proteasome inhibitor induced apoptosis in primary chronic lymphocytic leukemia cells.

"The proteasome inhibitors are a new class of antitumor agents. These inhibitors cause the accumulation of many proteins in the cell with the induction of apoptosis including TRAIL death receptors DR4 and DR5, but the role of the TRAIL apoptotic pathway in proteasome inhibitor cytotoxicity is unknown," wrote A.F. Kabore and colleagues, University of Manitoba.

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Source: Blood Weekly (2006-10-12)

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