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Stem Cell Research

Transcriptionally active umbilical cord blood-derived basophils isolated via purification

Published in Blood Weekly, October 12th, 2006

Transcriptionally active umbilical cord blood-derived basophils have been isolated via a purification method.

According to recent research from Sweden, "Basophils are inflammatory cells associated with allergy and parasite infections. Investigation of their true biological function has long been hampered by the difficulty in obtaining sufficient amounts of pure basophils and by the lack of phenotypic markers.

"Moreover, it has been very difficult to clone and identify basophil-specific granule proteins, partially because of an almost complete lack of mRNA in mature circulating basophils."

"To obtain transcriptionally active...

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