Published in Blood Weekly, October 19th, 2006
According to a study from Austria, "Chromosome arm 11q amplifications involving the mixed lineage leukemia gene (MLL) locus are rare but recurrent aberrations in AML and MDS. We have recently shown that in addition to the MLL core amplicon, independent sequences in 11q23-24 and/or 11q13.5 are coamplified within the same cytogenetic markers in 90% and 60% of patients, respectively."
"Here we further narrow down the minimal amplicon in...
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