Oncology
New data from Austria and Poland lluminates research in oncology
Published in Blood Weekly, October 19th, 2006
Study 1: GAB2 was proposed as a new target of 11q amplification in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
According to a study from Austria, "Chromosome arm 11q amplifications involving the mixed lineage leukemia gene (MLL) locus are rare but recurrent aberrations in AML and MDS. We have recently shown that in addition to the MLL core amplicon, independent sequences in 11q23-24 and/or 11q13.5 are coamplified within the same cytogenetic markers in 90% and 60% of patients, respectively."
"Here we further narrow down the minimal amplicon in...
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Source: Blood Weekly (2006-10-19)
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