Published in Blood Weekly, October 19th, 2006
"Using cell-based aptamer selection, we have developed a strategy to use the differences at the molecular level between any two types of cells for the identification of molecular signatures on the surface of targeted cells. A group of aptamers have been generated for the specific recognition of leukemia cells," investigators in the United States reported.
"The selected aptamers can bind to target cells with an equilibrium dissociation constant (K-d) in the nanomolar-to-picomolar range. The cell-based selection process is...
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