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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . October 26th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Angiology - Bivalirudin provides rapid and reliable anticoagulation during off-pump CABG

Tissue Engineering - Collagen synthesis by valve interstitial cells dependent upon stretch degree and duration

Tissue Engineering - Tissue engineering regenerates interdental papillae

Acute Myelogenous Leukemia - Juvaris wins innovation research grant for acute myelogenous leukemia vaccine development

Acute Myeloid Leukemia - Leukemogenic AML1-ETO-targeted proteins identified

Adenovirus Vector - Adenoviral vectors encoding bone morphogenetic protein-2 retarded bone formation

Angiology - Tranexamic acid should be used in off-pump coronary artery bypass grafting

Antitumor Therapy - Flavone from Cirsium japonicum DC inhibits tumors and improves immunity

Apoptosis - Apoptotic gene expression profiled in chronic lymphocytic leukemia

Asthma - Swedish researchers to study investigational outpatient procedure for asthma treatment

Atrial Fibrillation - Age affects major hemorrhage risk in atrial fibrillation patients regardless of warfarin status

Awards - EKOS to be honored as Tibbetts Award winner

Bacteriology - Bacterial bloodstream infections in cancer patients are changing and need further study

Bacteriology - Verax Biomedical initiates two external clinical trials to test for bacteria in platelets

Barrett Esophagus - Barrett esophagus ablation techniques investigated

Biomedical Engineering - Intravenous gas exchange device to treat acute lung failure is tested

Brain Cancer - Autocrine/paracrine platelet-derived growth factor regulates neural progenitor cell proliferation

Business Update - CyGenics Asian Healthcare announces expanded presence in Indonesia

Business Update - Dade Behring launches CardioPhase hsCRP test for use on its Stratus CS Acute Care Diagnostic System

Business Update - Daxor announces Alfieri Cardiology acquires Blood Volume Analyzer BVA-100

Business Update - Edwards Lifesciences launches LifeStent FlexStar and LifeStent FlexStar XL stent delivery systems

Cancer Gene Therapy - Transporter expression profiled in childhood T cell acute lymphoblastic leukemia

Cardiac Devices - Drug-eluting stent furor may be good news for Medical Ventures

Cardiology - Pediatric pneumatic pulsatile ventricular assist device implantation has improved

Cardiology - Ross operation selection factors for young patients are determined

Chronic Myeloid Leukemia - ABCG2 overexpression in chronic myeloid leukemia CD34+ cells is inhibited by imatinib mesylate

Diabetes Complications - Home and office blood pressure were not adequately controlled in most diabetic hypertensives

Diabetes Therapy - Pancreatic islet transplants revascularize when cocultured with angiogenesis stimulators beforehand

Drug Delivery - Colorimetric assays rapidly assess hydrogel-encapsulated cell designs

Drug Development - 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol trigger apoptosis in MDR1-expressing leukemia

Drug Development - Crystallographic analysis of Pieris' Anticalin targeting CTLA-4 confirms potential

Ebola Virus Vaccine - Crucell and NIH VRC announce start of Ebola vaccine clinical trial

Embryonic Stem Cell Research - Interleukin-3 is a proliferation and/or survival factor for earliest embryonic stem cells

Environmental Toxins - Electrical waste site cause of toxic pollutant biotransfer from mothers to newborns

Epstein-Barr Virus - 2B4 antibody is not suitable for the detection of Epstein Barr virus infection

Facilities - Human BioSystems to expand into larger research facility

Finance - Immtech collaborators receive $21.3M to fight trypanosomiasis and leishmania

Fungal Infections - Positive opinion issued for Noxafil Oral Suspension in preventing invasive fungal infections

Gene Delivery - Released DNA from oligo(poly(ethylene glycol) fumarate) composites retain bioactivity

Genetics & Genomics - Chronic lymphocytic leukemia biology influenced by p53 polymorphisms

Genetics & Genomics - Consortium develops map of vital area in major histocompatibility complex of human genome

Graft-versus-Host Disease - DOR BioPharma files NDA with U.S. FDA to market orBec for GI graft vs. host disease

Heart Transplantation - Axial flow pump advanced suction detection system is optimized

Heart Transplantation - Macroencapsulation protects against sensitization after islet transplantation

Hepatitis B Virus - Novartis' telbivudine therapy for patients with chronic hepatitis B receives Swiss approval

Hypotension - Meditor updates phase 2 trial on IV-administered drug for hypotension in hemodialysis

Injury Prevention - Childhood lead exposure is linked to increased teen injuries

Kaposi Sarcoma Therapy - Sirolimus is usually useful in post-transplantation Kaposi sarcoma management

Kidney Disease - Cyanotic nephropathy follows angiogenic activation

Leukemia - Childhood acute lymphoblastic leukemia linked to PTPN11 mutation

Leukemia - Chronic lymphocytic leukemia displays a proangiogenic component

Leukemia - Leukemia apoptosis induced by cisplatin

Leukemia - Leukemia incidence rates differ among races in the United States

Leukemia - Leukemia linked to infrequent Wnt inhibitory factor-1 (Wif-1) methylation

Leukemia - Leukemia patients find new hope in novel valproic acid derivatives

Leukemia - Leukemia treated by fludarabine, cytarabine, and mitoxantrone

Lung Transplantation - Noncritical coronary artery disease was not related to increased morbidity/mortality after lung transplant

Medical Devices - Implantable rotary blood pump noninvasive method detects pumping states

Medical Devices - Mini cardiopulmonary bypass air purge control is developed and tested

Multiple Myeloma - Patients with relapsed multiple myeloma show tolerance to tyrosine kinase inhibitor

Myocardial Infarction - Celera identifies genetic polymorphism associated with increased risk for myocardial infarction

Neurology - Intracerebral hematomas are lysed with implanted tissue plasminogen activator polymers

Paraganglioma - Paraganglioma treatment options should be investigated in Phase II trials

Pediatric Cardiology - RV and pulmonary function in sickle cell disease patients with pulmonary hypertension are described

Respiratory Medicine - Recombinant human activated protein C improves pulmonary function

Rheumatoid Arthritis - New dosages of etanercept in pre-filled syringes now available for arthritis, psoriasis

Sepsis Research - Interleukin-12 is critical to efficient host defense in polymicrobial sepsis

Stem Cell Research -  Stem Cells reports derivation of pluripotent human embryonic stem cells from non-viable embryos

Stem Cell Research - Akt promotes increased cardiomyocyte cycling and expansion of cardiac progenitor cells

Stem Cell Research - Bruno-like gene is required for stem cell maintenance in planarians

Stem Cell Research - Cancer stem cells exist in thyroid cancer

Stem Cell Research - Cytohesin binder and regulator not required for hematopoietic cell development or function

Stem Cell Research - Cytokine signals modulated via lipid rafts mimic niche signals and induce stem cell hibernation

Stem Cell Research - Early postnatal astroglial cells produce multilineage precursors and neural stem cells

Stem Cell Research - Embryonic stem cells may offer a means to facilitate vascular repair

Stem Cell Research - ViroPharma initiates first of two studies of maribavir in stem cell transplant patients

Stem Cell Transplantation - KIR ligand mismatch increases overall mortality in unrelated donor transplantation

Stem Cell Transplantation - Recipient B-cell precursors condition donor B-cell pool reconstitution after transplantation

Stroke - Stroke models receive benefits from therapy combining gene therapy with marrow cells

Thrombosis - Pericor Science announces advance in thrombin inhibitor research

Transplant Medicine - New transplant strategies may be pathway blockades, simultaneous use of immunosuppressants

Uremia - Hemodialysis acutely improves hepatic cytochrome P450 3A4 metabolic activity

Angiology - Recent studies from France, the New Zealand and Japan add new data to angiology research

Apoptosis - Research from the United States and Japan add new data to apoptosis body of knowledge

Aspergillosis - New findings from the United States in the area of aspergillosis described

Biomedical Engineering - Reports from the United Kingdom, Japan and United States describe recent advances in biomedical engineering research

Biomedical Engineering - Research from Singapore, the People's Republic of China and Taiwan in biomedical engineering provides new insights

Biomedical Engineering - Researchers from Taiwan, Italy and Australia publish new studies and findings in the area of biomedical engineering

Biomedical Engineering - Researchers from the United States detail new studies and findings in the area of biomedical engineering

Blood Banks - Findings from Brazil and the United States describe new data in blood banks research

Blood Banks - New findings in blood banks described from Australia, Spain and France

Cancer Treatment - Findings from Germany, Netherlands and the United States in cancer treatment provide new insights

Cancer Treatment - Studies from Israel, Canada and the United States advance knowledge in cancer treatment research

Cardiology - Reports from the United States and United Kingdom advance knowledge in cardiology research

Cardiology - Researchers from the United States detail new studies and findings in the area of cardiology

Cell Biology - New data from Canada and the United States lluminates research in cell biology

Cell Biology - Recent findings from Canada, the United States and Poland illuminate research in cell biology

Cell Biology - Reports from Italy, Japan and the United States advance knowledge in cell biology research

Cell Biology - Researchers from Spain and Japan report recent findings in cell biology

Cell Biology - Researchers from the United States, Spain and France report details of new studies and findings in the area of cell biology

Cell Biology - Researchers' findings from Japan and Scotland advance cell biology research

Cell Biology - Researchers' work from Turkey, Germany and Tunisia adds to cell biology body of knowledge

Cord Blood - Researchers' data from Taiwan, Australia and the United States advance cord blood research

Diabetes - Research from the United States, Netherlands and Japan in diabetes provides new insights

Gastric Cancer - Researchers from Japan and Sweden describe findings in gastric cancer studies

Genetics - Researchers from Japan, Belgium and the United States report recent findings in genetics

Hematology - Reports from Norway and the United States add new data to hematology research

Hepatitis C Virus - Findings from the United Kingdom and Italy describe new data in hepatitis C virus research

Hepatitis C Virus - Reports from France, the United Kingdom and Germany describe recent advances in hepatitis C virus research

Hepatitis C Virus - Researchers from Japan and Brazil detail new studies and findings in the area of hepatitis C virus

Hepatitis C Virus - Researchers' work from Japan, the United States and the United Kingdom adds to hepatitis C virus body of knowledge

Herpes - Researchers from Greece, Italy and Japan describe findings in herpes studies

Leukemia - Findings from Netherlands and South Korea advance knowledge in leukemia research

Leukemia - Findings from Netherlands, Belgium and Switzerland in leukemia provide new insights

Leukemia - New findings from Greece, the United States and Germany in the area of leukemia described

Leukemia - New findings from the United States and Italy in the area of leukemia detailed

Leukemia - New research from Germany and Japan in the area of leukemia detailed

Leukemia - New research from the United States and Brazil in the area of leukemia detailed

Leukemia - Recent findings in leukemia described by researchers from Canada, the United Kingdom and the United States

Leukemia - Reports from Brazil and Spain add new data to leukemia research

Leukemia - Researchers from the United States and United Kingdom report recent findings in leukemia

Leukemia - Researchers from the United States detail new studies and findings in the area of leukemia

Leukemia - Studies from South Korea, Germany and France describe new findings in leukemia research

Medical Devices - Research from the United States and Germany add new data to medical devices body of knowledge

Myeloma - Researchers from the United States publish new studies and findings in the area of myeloma

Neurology - Research from Japan and Brazil in neurology provides new insights

Neurology - Studies from Germany, the United States and France add new findings to neurology body of knowledge

Oncology - Recent studies from Germany and Japan add new data to oncology research

Oncology - Reports from the United States and Germany add new data to oncology research

Transplants - Findings from the United States and Canada describe new data in transplants research

Transplants - Reports from the United States advance knowledge in transplants research

Transplants - Research from the United States, Spain and Norway in transplants provides new insights

Transplants - Researchers from Italy, Switzerland and the United Kingdom detail new studies and findings in the area of transplants

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