Leukemia

Findings from Netherlands and South Korea advance knowledge in leukemia research

Published in Blood Weekly, October 26th, 2006

Reports from Netherlands and South Korea highlight recent research in leukemia.

Study 1: Fms-like tyrosine kinase 3/ITD is a relevant marker for acute myeloid leukemia prognosis.

According to recent research from the Netherlands, "In acute myeloid leukemia (AML), activating mutations in the fms-like tyrosine kinase 3 (FLT3) gene predict poor prognosis. We determined FLT3 internal tandem duplications (FLT3/ITD) and D835 point mutations in paired initial and relapse samples from 80 pediatric and adult AML patients."

"One D835 point mutation was found in an initial pediatric AML sample. Fms-like tyrosine kinase 3/ITDs were present in...

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Source: Blood Weekly (2006-10-26)

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