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Ischemia

Ischemia reperfusion injury involves modulation of benzodiazepine receptor

Published in Blood Weekly, November 2nd, 2006

Recent research from France has reported on the modulation of peripheral-type benzodiazepine receptor (PBR) during ischemia reperfusion injury in a pig kidney model.

"It was demonstrated that postischemic kidney expresses different factors in a pattern that recapitulates expression of these factors in the developing kidney," wrote K.Q. Zhang and colleagues, CHU Poitiers.

"We investigated whether peripheral-type benzodiazepine receptor (PBR), which belongs to the mitochondrial permeability transition pore and is essential during development, could be influenced by the ischemia-reperfusion injury process when compared with leukemia inhibitor factor...

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