Sepsis Therapy

Research reports from University of Michigan, Department of Pathology provide new insights into sepsis therapy

Published in Blood Weekly, November 9th, 2006

New investigation results, "Mechanisms of mortality in early and late sepsis," are detailed in a study published in Infection and Immunity. According to a study from the United States, "A recent hypothesis postulates that sepsis moves through different phases, with periods of enhanced inflammation alternating with periods of immune suppression. In this study we determined the levels of inflammation present during early and late septic deaths to examine whether death was due to hyperinflammation or immunosuppression."

"The murine model of sepsis induced by cecal ligation and puncture (CLP) was used. Complete blood counts, plasma interleukin-6 (IL-6) levels, and body...

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Source: Blood Weekly (2006-11-09)

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