Hodgkin Lymphoma Therapy

Interferon-alpha therapy has activity in children with advanced Hodgkin lymphoma

Published in Blood Weekly, November 9th, 2006

Interferon-alpha therapy has activity in children with advanced Hodgkin lymphoma.

According to a recent study from the United States, "Thirteen children with refractory or recurrent Hodgkin's lymphoma (HL) received high-dose chemotherapy and autologous hematopoietic stem cell transplant (ASCT).

"After hematologic recovery, 10 patients were given interferon-a (IFN-alpha) as adjuvant therapy, starting at a dose of 0.5x10⁶ U/m² subcutaneously, three times a week. The dose was escalated as tolerated. Patients were treated for a median of 12 (4-24) months."

"Transient myelosuppression was the most common toxicity...

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Source: Blood Weekly (2006-11-09)

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