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Tissue Engineering

Three-dimensional tissue-engineered bone fabricated in a rotating bioreactor

Published in Blood Weekly, November 16th, 2006

Three-dimensional tissue-engineered bone has been fabricated in a rotating bioreactor.

According to recent research from the People's Republic of China, "In order to explore the methods for commercialized bone tissue engineering, engineered bones should be cultivated in bioreactors to realize 3-dimensional culture under well-defined culture conditions.

"In the present paper, osteoblasts isolated from the cranium of 1-month-old Zelanian rabbits were inoculated on to the BDBS (bioderived bone scaffolds) to investigate the 3-dimensional fabrication of engineered bone in an RWVB (rotating-wall vessel bioreactor)."

"The osteoblasts,...

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