Published in Blood Weekly, November 16th, 2006
"Total Therapy 1, the first tandem autotransplant trial for newly diagnosed patients with multiple myeloma, was designed to increase the frequency of complete response (CR) and thereby extend survival. With a median follow-up of 12 years, 62 of 231 initially enrolled patients are alive (17% at 15 years); 31 remain event free (7% at 15 years) including 16 of 94 (41%) that initially achieved CR," according to investigators in the United States.
"Currently alive patients less frequently had cytogenetic abnormalities (CAs) at baseline (p=.002),...
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