Gene Therapy
Research in the area of gene therapy reported from Heart Institute
Published in Blood Weekly, November 30th, 2006
New investigation results, "Skeletal muscle cells expressing VEGF induce capillary formation and reduce cardiac injury in rats," are detailed in a study published in International Journal of Cardiology. "We tested a preemptive combined cell/gene therapy strategy of skeletal myoblasts transfected with Ad(5)RSVVEGF-165 in an ischemia/reperfusion rat model to increase collateral blood flow to nonischemic heart tissue. Lewis rats were injected with placebo (Control), 106 skeletal myoblasts (SkM), or 106 skeletal myoblasts transfected with Ad(5)RSVVEGF-165 (SkM(+)) into the left ventricle 1week before ischemia," scientists writing in the International Journal of...
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Source: Blood Weekly (2006-11-30)
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