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Gastric Cancer

Recent studies from Japan and the People's Republic of China add new data to gastric cancer research

Published in Blood Weekly, November 30th, 2006

Investigators in Japan and the People's Republic of China have published new gastric cancer data.

Study 1: Chemosensitivity of gastric cancer to anticancer drugs could be increased by the histone deacetylase inhibitor trichostatin A (TSA).

According to a study from Japan, "Epigenetic alterations of the histone acetylation play an important role in the regulation of gene expression associated with cell cycles and apoptosis that may affect the chemosensitivity of gastric carcinomas. Recently, a histone deacetylase inhibitor, TSA, was proven to be a chemo-sensitizer on human erythroleukemia cells."

"With the aim of improving the...

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