Published in Blood Weekly, November 30th, 2006
Study 1: Chemosensitivity of gastric cancer to anticancer drugs could be increased by the histone deacetylase inhibitor trichostatin A (TSA).
According to a study from Japan, "Epigenetic alterations of the histone acetylation play an important role in the regulation of gene expression associated with cell cycles and apoptosis that may affect the chemosensitivity of gastric carcinomas. Recently, a histone deacetylase inhibitor, TSA, was proven to be a chemo-sensitizer on human erythroleukemia cells."
"With the aim of improving the...
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Source: Blood Weekly (2006-11-30)
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