Sepsis
Researchers from University of Florida, Department of Surgery discuss findings in sepsis
Published in Blood Weekly, December 28th, 2006
New research, "Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis," is the subject of a report. "Regulatory T cells (Tregs), including natural CD4+CD25+ Tregs and inducible IL-10 producing T regulatory type 1 (T(R)1) cells, maintain tolerance and inhibit autoimmunity. Recently, increased percentages of Tregs have been observed in the blood of septic patients, and ex vivo-activated Tregs were shown to prevent polymicrobial sepsis mortality," scientists writing in the Journal of Immunology report.
"Whether endogenous Tregs contribute to sepsis outcome remains unclear....
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Source: Blood Weekly (2006-12-28)
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