Thrombocytopenia Immunology
Data on thrombocytopenia immunology reported by researchers at Institute for Transfusion Medicine
Published in Blood Weekly, January 11th, 2007
Data detailed in "CD47 is expressed at normal levels in patients with autoimmune haemolytic anaemia and/or immune thrombocytopenia" have been presented. "CD47 deficiency results in lethal autoimmune haemolytic anaemia (AIHA) and mild spontaneous thrombocytopenia in non-obese diabetic mice. It is unknown whether CD47 has an impact on AIHA of the warm type or autoimmune thrombocytopenia (ITP) in humans," researchers in Berlin, Germany report.
"Healthy blood donors (n=11), patients with AIHA (n=13), patients with ITP (n=18) and one patient with Rh(null) phenotype were investigated. CD47 expression on red blood cells (RBC), platelets, granulocytes and lymphocytes and in...
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Source: Blood Weekly (2007-01-11)
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