Transfusion Medicine
New transfusion medicine study findings recently were published by researchers at University Hospital, Department of Transfusion Medicine
Published in Blood Weekly, January 18th, 2007
Scientists discuss in "In-frame triplet deletions in RHD alter the D antigen phenotype" new findings in transfusion medicine. "The deletion of three adjacent nucleotides in an exon may cause the lack of a single amino acid, while the protein sequence remains otherwise unchanged. Only one such in-frame deletion is known in the two RH genes, represented by the RHCE allele ceBP expressing a "very weak e antigen." STUDY Blood donor samples were recognized because of discrepant results of D phenotyping," scientists in Ulm, Germany report.
"Six samples came from Switzerland and one from Northern Germany. The molecular structures were determined by genomic DNA nucleotide...
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Source: Blood Weekly (2007-01-18)
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