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Kidney Transplants

New kidney transplants study findings recently were published by researchers at General Hospital, Department of Clinical Pharmacology

Published in Blood Weekly, January 25th, 2007

Research findings, "Influence of CYP3A5 genetic polymorphism on cyclosporine A metabolism and elimination in Chinese renal transplant recipients," are discussed in a new report. In this recent article published in the journal Acta Pharmacologica Sinica, scientists in Nanjing, People's Republic of China conducted a study "To investigate whether the CYP3A5*3 polymorphism would affect cyclosporine A (CsA) metabolism in Chinese renal transplant patients. The CYP3A5*3 genotype was determined in Chinese renal transplant recipients using polymerase chain reaction and amplification of specific alleles (PCR-ASA)."

"The concentrations of CsA and metabolites were separately...

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