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Hemorrhagic Shock

New hemorrhagic shock research has been reported by scientists at University of Sao Paulo

Published in Blood Weekly, March 8th, 2007

Investigators publish new data in the report "Hypertonic saline solution increases the expression of heat shock protein 70 and improves lung inflammation early after reperfusion in a rodent model of controlled hemorrhage. Hypertonic saline solution (HS solution, NaCl 7.5%) has shown to restore hemodynamic parameters in hemorrhagic shock and to decrease the inflammation triggered by ischemia-reperfusion injury (I-R). Therefore, our objective was to investigate the effects of HS solution on the mechanisms involved in I-R, in an experimental model of controlled hemorrhagic shock," investigators in Sao Paulo, Brazil report.

"Wistar rats (280-350 g) were submitted to...

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