Ischemia
Researchers from Innsbruck Medical University, Division of Nephrology provide details of new studies and findings in the area of ischemia
Published in Blood Weekly, March 8th, 2007
Scientists discuss in "p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury" new findings in ischemia. "In many clinical settings, the duration of renal ischemia and therefore the outcome of acute renal failure cannot be determined adequately. Renal ischemia reperfusion injury is known to shorten telomeres and upregulate stress-induced genes, such as the cyclin-dependent kinase (CDK) inhibitor p21," scientists in Innsbruck, Austria report.
"So far, the expression and role of CDK inhibitors, as well as mouse telomerase reverse transcriptase (mTERT), has not been investigated in a model with variable lasting...
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Source: Blood Weekly (2007-03-08)
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